Facile synthesis of β‐cyclodextrin‐grafted solid silica nanoparticles

Abstract

In this work, a simple and reliable method for the synthesis of β-cyclodextrin (β-CD)-grafted silica nanoparticles (SiNPs) is developed. The synthetic protocol included postsynthesis functionalization of silica nanoparticles with aminopropyl trimethoxysilane (APTES) followed by the condensation of the amino groups with imidazole carbamate ester of β-CD. The activated β-CD (carbamate ester) was prepared by reacting it with carbonyldiimidazole (CDI). The grafting of (β-CD) on SiNPs was confirmed by ATIR-IR, DLS, and TGA analyses. The method developed can be easily reproduced with any other oxide nanoparticles for the preparation of β-CD-grafted nanoparticles.

Mechanochemical green synthesis of hyper-crosslinked cyclodextrin polymers

“…They have a slightly different structures (and color), and also different surface charges but share a reactive nucleophilic carboxylic group. The simplified schematic reaction (previously reported by Staab [ 31 ] and more recently by Jadhav et al [ 33 ]), with the relative ζ-pot of nanoparticles after functionalization, is presented in Fig. 8 .…”

Dynamic in situ growth of bonded-phase silica nanospheres on silica capillary inner walls for open-tubular liquid chromatography

“…The surface of the SNS was first modified with amino groups, to provide a proper reactive spacer group, as demonstrated by Jadhav et al [ 35 ]. For this purpose, an SNS-coated fused silica capillary column was flushed with a mixture of APTES (250 µL) and n-propylamine (2 µL) in cyclohexane (10 mL) for 15 min and then it was sealed at both ends using GC septa and kept in an oven at 60 °C for 1 h. Afterwards, the column was washed with acetone to remove nongrafted APTEPS and other impurities.…”