Facile Synthesis and Antioxidant Evaluation of 4-Arylmethylideneisoxazol-5(4<i>H</i>)-ones

Laroum, Rima; Boulcina, Raouf; Bensouici, Chawki; Debache, Abdelmadjid

doi:10.1080/00304948.2019.1677993

Cited by 15 publications

(2 citation statements)

References 18 publications

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“…Several other inorganic catalysts such as ceria‐doped zirconia (CeO 2 /ZrO 2 ), [ 97 ] sodium citrate (5 mol%), [ 98 ] SBA/hydrotalcite/heteropolyacid nanocomposite (LDH/SBA/HPA). [ 99 ] and MIL‐53(Fe) metal‐organic frameworks.…”

Section: Review Of the Literaturementioning

confidence: 99%

Synthesis of pyrano[2,3‐c]pyrazoles: A review

Sikandar

Zahoor

2020

Journal of Heterocyclic Chem

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One‐pot synthesis of pyrano[2,3‐c]pyrazole derivatives via two or multicomponent condensation of β‐ketoesters, hydrazine monohydrate/phenyl hydrazine, malononitrile, and substituted benzaldehydes is of great interest not only in synthetic chemistry but also in medicinal chemistry because of the tremendous biological activities, such as anticancer, anti‐inflammatory, analgesic, antimicrobial, and enzyme inhibitory activities exhibited by pyranopyrazoles. This review provides extensive knowledge on novel synthetic methodologies of biologically active non‐spiro/spiro‐pyrano[2,3‐c]pyrazole derivatives published recently.

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Section: Review Of the Literaturementioning

confidence: 99%

Synthesis of pyrano[2,3‐c]pyrazoles: A review

Sikandar

Zahoor

2020

Journal of Heterocyclic Chem

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“…The main method of synthesis is the Knoevenagel reaction between rhodanine and aldehydes in the presence of various catalysts, such as, for example, ammonium acetate, 27 2-hydroxyethylammonium acetate, 28 NaOAc/HOAc, 29 2,2,6,6-tetramethyl piperidine, 30 glycine, 31 1-butyl-3-methyl imidazolium hydroxide, 32 NH 4 Cl/NH 4 OH, 33 piperidine, 34 supported K 2 CO 3 on Al 2 O 3 under microwave irradiation 35 or in the presence of an ionic liquid. 36 As a continuation of our research for an new environment-friendly approaches, [37][38][39] we herein propose a new simple and ecocompatible procedure for the preparation of 5-arylidene rhodanines using Na 2 SO 3 as catalyst in EtOH at reflux under conventional heating (Scheme 1). The hydrolysis of some of them was carried out in a second step to provide the corresponding 2-mercapto-3-substituted-acrylic acids 4.…”

Section: Introductionmentioning

confidence: 99%

Facile synthesis of 5-arylidene rhodanine derivatives using Na2SO3 as an eco-friendly catalyst. Access to 2-mercapto-3-aryl-acrylic acids and a benzoxaborole derivative

Boureghda¹,

Boulcina²,

Dorcet

et al. 2021

Tetrahedron Letters

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Magnetic nanoparticle supported choline chloride-glucose (deep eutectic solvent) for the one-pot synthesis of 3,4-disubstituted isoxazol-5(4H)-ones

Atharifar,

Keivanloo,

Maleki

et al. 2023

Res Chem Intermed

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One e cient method for the synthesis of 3,4-disubstituted isoxazole-5(4H)-ones derivatives catalyzed magnetic deep eutectic solvent is reported. The structure of the nano-catalyst was characterized by FE-SEM, FT-IR, EDX, and TGA. Then, the excellent activity of the catalyst was displayed for the synthesis of 3,4-disubstituted isoxazole-5(4H)-ones derivatives. This heterogeneous catalyst can be easily recovered via a magnetic eld and reused for subsequent reactions. Easy workup, high yields in a short time and non-toxic catalyst are the main merits of this method.

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Facile Synthesis and Antioxidant Evaluation of 4-Arylmethylideneisoxazol-5(4H)-ones

Cited by 15 publications

References 18 publications

Synthesis of pyrano[2,3‐c]pyrazoles: A review

Synthesis of pyrano[2,3‐c]pyrazoles: A review

Facile synthesis of 5-arylidene rhodanine derivatives using Na2SO3 as an eco-friendly catalyst. Access to 2-mercapto-3-aryl-acrylic acids and a benzoxaborole derivative

Magnetic nanoparticle supported choline chloride-glucose (deep eutectic solvent) for the one-pot synthesis of 3,4-disubstituted isoxazol-5(4H)-ones

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