Facile Coordination-Precipitation Route to Insoluble Metal Roussin’s Black Salts for NIR-Responsive Release of NO for Anti-Metastasis

Chen, Lijuan; He, Qianjun; Lei, Minyi; Xiong, Liwei; Shi, Kun; Tan, Liwei; Jin, Zhaokui; Wang, Tianfu; Zhang, Qian

doi:10.1021/acsami.7b11325

Cited by 26 publications

(25 citation statements)

References 29 publications

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“…Upon NIR (808 nm) laser irradiation, the photothermal conversion of polydopamine layer rapidly increased the local temperature and triggered the NO release from SNO (Figure e), which further reversed the MDR of MCF‐7/ADR cancer cells, enhanced the chemotherapeutic efficacy of DOX, and caused photoinduced hyperthermia as indicated by the significantly inhibited tumor growth (Figure f) . Qian et al reported a facile coordination–precipitation approach to fabricate insoluble metal Roussin's black salts, which performed a NIR adsorption‐dependent NIR‐responsive NO releasing for significantly inhibiting the growth and metastasis of metastatic breast cancer …”

Section: Nitric Oxide (No)‐generating Ggnsmentioning

confidence: 99%

Gas‐Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

2018

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The fast advances of theranostic nanomedicine enable the rational design and construction of diverse functional nanoplatforms for versatile biomedical applications, among which gas-generating nanoplatforms (GGNs) have emerged very recently as unique theranostic nanoplatforms for broad gas therapies. Here, the recent developments of the rational design and chemical construction of versatile GGNs for efficient gas therapies by either exogenous physical triggers or endogenous disease-environment responsiveness are reviewed. These gases involve some therapeutic gases that can directly change disease status, such as oxygen (O ), nitric oxide (NO), carbon monoxide (CO), hydrogen (H ), hydrogen sulfide (H S) and sulfur dioxide (SO ), and other gases such as carbon dioxide (CO ), dl-menthol (DLM), and gaseous perfluorocarbon (PFC) for supplementary assistance of the theranostic process. Abundant nanocarriers have been adopted for gas delivery into lesions, including poly(d,l-lactic-co-glycolic acid), micelles, silica/mesoporous silica, organosilica, MnO , graphene, Bi Se , upconversion nanoparticles, CaCO , etc. Especially, these GGNs have been successfully developed for versatile biomedical applications, including diagnostic imaging and therapeutic use. The biosafety issue, challenges faced, and future developments on the rational construction of GGNs are also discussed for further promotion of their clinical translation to benefit patients.

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Section: Nitric Oxide (No)‐generating Ggnsmentioning

confidence: 99%

Gas‐Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

2018

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“…[117] Since gasotransmitters can serve as endogenous gaseous messengers to regulate physiological functions, gas therapy is considered a "green" treatment paradigm that has negligible side effects on normal tissues. NO gasotransmitters have direct antitumor effects at high concentrations; therefore, encapsulating NO donors (e.g., nitroimidazole, [118] S-nitrosothiol (SNO), [86a] and Roussin's black salt (RBS) [119] ) into lanthanide nanoparticles seems to be a promising approach to control the NO concentration for X-ray-induced gas therapy because lanthanide nanoparticles can act as a scintillator and convert high-energy X-rays into UV-vis light, further triggering NO release from NO donors. Reproduced with permission.…”

Section: X-ray-activated Gas Therapymentioning

confidence: 99%

Progress in Light‐Responsive Lanthanide Nanoparticles toward Deep Tumor Theranostics

Yan

Yang

et al. 2021

Adv Funct Materials

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Recently, lanthanide nanoparticles have aroused widespread interest in cancer theranostics by virtue of their excellent photoresponsive performance in deep-seated tumors. The abundant ladder-like energy levels, controllable emission profiles, and unique photoluminescence properties make lanthanide nanoparticles highly efficient for deep skin-penetration of near-infrared (NIR) light, concentrating light energy in tumors with negligible scattering and minimal autofluorescence from biological tissues. High-Z radio-sensitization of lanthanide elements endows lanthanide nanoparticles with a high X-ray attenuation coefficient, making them effective nanoprobes for X-ray-excited bioimaging and synchronous radiotherapy-related treatments. In this review, comprehensive progressions including the synthesis, structural characteristics of lanthanide nanoparticles, and distinct optical excitation mechanisms with NIR and X-ray triggers, are summarized. Advances in NIR-excited and X-ray-triggered cancer imaging methods and therapies are described in detail, wherein NIR-induced luminescence from upconversion nanoparticles and downconversion nanoparticles are introduced separately based on some typical sensitization. Finally, the challenges and opportunities of lanthanide nanoparticles as light-triggered cancer theranostic candidates are discussed, whose translation from bench to bedside still has a long journey to go.

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“…The NIR‐responsive nanomedicine had been widely studied in recent years (L. Chen et al, ; J. Peng et al, ; X. Tang et al, ). For example, a mesoporous magnetic gold “nanocluster” (MMGNCs) was built to load doxorubicin (DOX) in 2014 (J. Peng et al, ).…”

Section: Physical‐responsive Nanomedicinementioning

confidence: 99%

Physical‐, chemical‐, and biological‐responsive nanomedicine for cancer therapy

Liao

Jia

et al. 2019

WIREs Nanomed Nanobiotechnol

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Cancer therapy is unsatisfactory as it typically has serious side effects, because normal cells in healthy organs are destroyed along with the tumor. Thus, researchers have tried to develop effective therapies with minimal side effects. One such method is to use nanotechnology to carry the drugs or therapeutic agents to the tumor region by secure encapsulation without leakage. Once the nanomedicine enters the target tumor site, it can release therapeutic agents in an effective manner. Accordingly, various nanomedicines have been developed to enhance the efficiency of cancer therapy and minimize the systematic toxicity. Here, we provide an overview and discuss the different types of responsive nanomedicines including physically, chemically, biologically, dual, and multi‐responsive nanomedicines, for the in situ release of cargos in recent years. We propose critical considerations that must be considered for the design of excellent stimuli‐nanomedicine. Furthermore, the possible directions for the development of successful stimuli‐responsive (smart) nanomedicine are highlighted. With the development of responsive nanomedicines, precise and personalized nanomedicine will be realized with great promise in the future. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease Nanotechnology Approaches to Biology > Nanoscale Systems in Biology

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Facile Coordination-Precipitation Route to Insoluble Metal Roussin’s Black Salts for NIR-Responsive Release of NO for Anti-Metastasis

Cited by 26 publications

References 29 publications

Gas‐Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

Gas‐Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

Progress in Light‐Responsive Lanthanide Nanoparticles toward Deep Tumor Theranostics

Physical‐, chemical‐, and biological‐responsive nanomedicine for cancer therapy

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