Facile aqueous synthesis of Ni-doped CdTe quantum dots as fluorescent probes for detecting pyrazinamide in plasma

Safari, Meysam; Najafi, S. Iraj; Arkan, Elham; Amani, Saeid; Shahlaei, Mohsen

doi:10.1016/j.microc.2019.01.019

Cited by 25 publications

(17 citation statements)

References 34 publications

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“…The general approach for the synthesis of Pt: CdTe d-dots was performed by the previous procedure ( Najafi et al, 2018 ; Safari et al, 2019 ). At first, sodium hydrogen telluride (NaHTe) was prepared by reducing Te powder with NaBH 4 in deionized water under stirring conditions and N 2 purging.…”

Section: Methodsmentioning

confidence: 99%

A Sandwich-Type Electrochemical Immunosensor Using Antibody-Conjugated Pt-Doped CdTe QDs as Enzyme-Free Labels for Sensitive HER2 Detection Based on a Magnetic Framework

Ehzari

Safari

2022

Front. Chem.

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Tumor markers are highly sensitive and play an important role in the early diagnosis of cancer. We developed an electrochemical sandwich-type immunosensor that detects human epidermal growth factor receptor 2 (HER2). Magnetic framework (Fe3O4@ TMU-24) and AuNPs (Fe3O4@ TMU-24 -AuNPs) are utilized in this sensing platform. In addition to their high specific surface area and excellent biocompatibility, Fe3O4@ TMU-24-AuNPs nanocomposites exhibited excellent electrocatalytic properties. The primary antibody of HER2 (Ab1) was immobilized on the surface of the Fe3O4@ TMU-24-AuNPs. In this sensing method, palatine doped to CdTe QDs (Pt: CdTe QDs) is utilized as a novel labeling signal biomolecule (secondary antibodies). Pt: CdTe QDs own good biocompatibility and excellent catalytic performance. The amperometric technique was used to achieve the quantitative determination of HER2 by using a sandwich-type electrochemical immunosensor. Under the optimum conditions, the dependency of the current signal and HER2 concentration showed a linear region from 1 pg ml−1–100 ng ml−1 with 0.175 pg ml−1 as the limit of detection. This biosensing device also showed long stability and good reproducibility, which can be used for the quantitative assay of HER2.

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Section: Methodsmentioning

confidence: 99%

A Sandwich-Type Electrochemical Immunosensor Using Antibody-Conjugated Pt-Doped CdTe QDs as Enzyme-Free Labels for Sensitive HER2 Detection Based on a Magnetic Framework

Ehzari

Safari

2022

Front. Chem.

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“…2019 [21] protocols with few modifications together with the solvents and reagents were utilized. In a brief reaction, SOL A was prepared with 1 M Se in 5 ml TBP and held under inert gas at room temperature.…”

Section: Synthesis Of Cdse Qds With Ni 2+ Dopantmentioning

confidence: 99%

“…For the influential models of dopants, Ni is considered a stable and most efficient dopant for the QDs that shows ferromagnetic natures compared with other metal dopants. [21] The presence of dopants in the QDs to be tuned for potential applications by enhancing features including magnetic and electrical properties. [22][23][24] The quantum confinement effect changes the electronic structure of nanocrystals when their diameter is comparable with or less than that of a bulk exciton.…”

Section: Introductionmentioning

confidence: 99%

Biocompatible Ni‐doped CdSe/ZnS semiconductor nanocrystals for cellular imaging and sorting

et al. 2022

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Quantum dots (QD) with chemical composition QD 650CdSe=ZnS_Ni were successfully synthesized using a hydrothermal method and chemical precipitation. The nanocrystalline phase of the nanostructures was isolated and characterized using X-ray diffraction (XRD). The mean crystalline size doped core/shell Ni-dopant range was 9.0 ± 2.0 nm. The ferromagnetic data revealed the magnetic behaviour of QD 650CdSe=ZnS_Ni . The optical absorption measurements of these QDs were in the UV-visible light range 200-800 nm for a band gap value of 2.11 eV for QD 650 CdSe=ZnS_Ni . This means that pure QD 650CdSe and QD 650 CdSe=ZnS_Ni underwent a redshift when compared with bulk CdSe. For QD 650CdSe=ZnS_Ni there was successful uptake by cell lines including HeLa and MCF-7 for bioimaging and sorting applications.

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“…35 The toxicity of Cd-based QDs can be reduced through structural engineering such as doping transition metal ions in order to reduce the ratio of toxic Cd in undoped QDs. 36 Furthermore, manufacturing high-quality core-shell QDs can reduce the toxicity of heavy-metal-based QDs. Core-shell QDs are very desirable for many biological applications, as they have improved fluorescence properties and prevent leaching; however, their toxicity is still a major concern for in vivo studies in particular.…”

Section: Introductionmentioning

confidence: 99%

Gateway towards recent developments in quantum dot-based light-emitting diodes

et al. 2022

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Facile aqueous synthesis of Ni-doped CdTe quantum dots as fluorescent probes for detecting pyrazinamide in plasma

Cited by 25 publications

References 34 publications

A Sandwich-Type Electrochemical Immunosensor Using Antibody-Conjugated Pt-Doped CdTe QDs as Enzyme-Free Labels for Sensitive HER2 Detection Based on a Magnetic Framework

A Sandwich-Type Electrochemical Immunosensor Using Antibody-Conjugated Pt-Doped CdTe QDs as Enzyme-Free Labels for Sensitive HER2 Detection Based on a Magnetic Framework

Biocompatible Ni‐doped CdSe/ZnS semiconductor nanocrystals for cellular imaging and sorting

Gateway towards recent developments in quantum dot-based light-emitting diodes

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