Facile and versatile strategy to prepare magnetic molecularly imprinted particles based on the coassembly of magnetic nanoparticles and amphiphilic random copolymers

Abstract

Magnetic molecularly imprinted polymer nanoparticles for bisphenol A were prepared by coassembling magnetic nanoparticles and amphiphilic random copolymers. Under optimized conditions, bisphenol A as template molecules, magnetic molecularly imprinted polymer particles with regular morphology, small size, good monodispersity, and high content of OA-Fe O were prepared by the coassembly method using P(MMA-co-MAA) with monomer ratio of 9:1. These magnetic molecularly imprinted polymer particles could be rapidly collected by an external magnet within 1 min. The saturated adsorption capacity of the magnetic molecularly imprinted polymer for bisphenol A was 201.5 mg/g, and the imprinting factor was 2.5. The separation factors for bisphenol A to β-estradiol, estriol, and diethylstilbestrol was 3.1, 2.9, and 3.7, respectively. Unlike assembling amphiphilic copolymer in the selective solvent, the coassembly process was simple and rapid. Therefore, the present work provided a facile and versatile approach to construct magnetic molecularly imprinted polymer nanoparticles under mild conditions.

Combined biocompatible medium with molecularly imprinted polymers for determination of aflatoxins B1 in real sample

“…And MIPs were also combined with supporting materials to achieve better extraction effects. Such as, MIPs combined with covalent organic frameworks were applied in food and plants samples ; Amphiphilic magnetic MIPs were prepared and used to extract chloroacetamide herbicides and bisphenol A .…”

Preparation and evaluation of temperature and magnetic dual‐responsive molecularly imprinted polymers for the specific enrichment of formononetin

“…In particular, magnetic‐sensing and thermo‐responsive MIPs have been developed and displayed broad application prospects in drug delivery systems, sensors, and separation technology . Magnetic molecularly imprinted polymers (MMIPs) are prepared by coating MIP film on the surface of magnetic nanoparticles, such as Fe 3 O 4 and γ‐Fe 3 O 4 , resulting in MMIPs combining the advantages of molecular recognition and fast magnetic separation .…”