Facile and Mild Deboronation ofo-Carboranes Using Cesium Fluoride

The first examples of platinum(II)-amine complexes containing 1,2-dicarba-closo-dodecaborane(12)

“…195 Pt{ 1 H} NMR studies confirmed the initial formation of the expected cis-dichloro species by the presence of a singlet at approximately d )2100, consistent with a PtCl 2 N 2 core [4]. However, 11 B{ 1 H} NMR studies indicated a gradual increase in the formation of a nido-7,8-carborane species due to an expulsion of the B-3 atom from the corresponding closo-1,2-carborane structure [5]. The deboronation of closo-1,2-carborane ligands has previously been observed in the preparation of palladium(II) complexes containing 1,2-(PR 2 ) 2 -1,2-C 2 B 10 H 10 (R ¼ aryl, alkyl, alkoxy) [6] and copper(I) and gold(I) derivatives of 1-PPh 2 -2-SR-1,2-C 2 B 10 H 10 (R ¼ Et, Bz) [7] in the presence of nucleophilic solvents such as EtOH.…”

Nucleoside-metallacarborane conjugates - synthesis of a uridine - bearing 3,3,3-(CO)3-closo-3,1,2-ReC2B9H10 complex

“…[25][26][27] Reports on the direct formation of metallacarboranes from closo-carboranes were published by Hawthorne. 28 Re-carborane complexes can be prepared in aqueous solution using different sources of fluoride ions to degrade closo-carboranes to yield nido-carboranes to facilitate the formation of the desired Recarborane complexes directly from the closo forms.…”

Carboranylporphyrazines for anti-cancer therapies: synthesis and physicochemical properties

“…During this step, the o-carborane cages, owing to their sensitivity to even moderately strong nucleophiles -including the templating agent Mg II (n-OPr) 2 in n-PrOH -may undergo significant chemical and structural changes, affording complex mixtures of anionic (nido) species. It is well known, indeed, that treatment of o-carboranes with different nucleophiles, including alkaline-metal alkoxides, represents a useful synthetic tool for inducing the closo→nido conversion of the carborane cage [57][58][59][60][61][62].…”