Facial Cutaneous Metastasis in Renal Cell Carcinoma

Lorenzo-Ríos, Deyson; Cruzval-O’Reilly, Estefanía; Rabelo-Cartagena, Jose

doi:10.7759/cureus.12093

Cited by 2 publications

(3 citation statements)

References 17 publications

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“…Advanced GSRC is commonly considered to have a poor prognosis and inferior chemosensitivity compared to other types of gastric cancer (16). In general, it has often been recommended that patients diagnosed with cutaneous metastasis should undergo surgical resection of the skin lesion even as a palliative treatment option (2,13,17). Due to the fact that our patient complained of the so-called 'numb-chin syndrome' with intermittent neuropathic pain, palliative surgery seemed to be a valuable option knowing that many cutaneous metastases show rapid progression with bleeding and ulceration.…”

Section: Discussionmentioning

confidence: 99%

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Facial Cutaneous Metastases of Gastric Signet-ring Cell Carcinoma: Resection and Reconstruction as a Palliative Surgical Treatment Option

Eckardt¹,

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2022

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Background: Cutaneous metastases of gastric signet-ring cell gastric carcinoma are very rare. Our following case report highlights the need for careful clinical examination and skin biopsy of newly developing scar-like or erythematous skin lesions in patients with a known history of malignant disease in order to prevent diagnostic and therapeutic delay. Case Report: A 68-year-old male patient presented with two slightly painful, erythematous, facial skin lesions (chin and forehead) 2 years after gastrectomy for a signet-ring cell gastric carcinoma. The patient complained of intermittent neuropathic pain in the area of the mental nerve. A biopsy of both skin lesions demonstrated metastasis of signet-ring cell gastric carcinoma. Following discussion within the multidisciplinary tumor board, palliative surgical excision was recommended for this patient. Both skin lesions were resected and the large defect in the chin region was primarily closed by a cervical skin transposition flap. Conclusion: The presented case report of a patient with a known history of malignancy illustrates that newly developing erythematous skin lesions may be suspicious for cutaneous metastases. Palliative surgical interventions may play a role even in an advanced disease stage.

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Section: Discussionmentioning

confidence: 99%

“…Cutaneous metastases of solid tumors occur with variable frequency, with reported incidence rates from 0.7% to 9.0% (1,2). A meta-analysis of patients with visceral malignancies revealed an incidence of skin metastasis of 5.3% (3).…”

mentioning

confidence: 99%

Facial Cutaneous Metastases of Gastric Signet-ring Cell Carcinoma: Resection and Reconstruction as a Palliative Surgical Treatment Option

Eckardt¹,

Back²

2022

In Vivo

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show abstract

“…3 Although they are generally detected within 5 years from the primary tumor diagnosis, skin metastases occasionally develop decades later. 4 The preferred approach for single, isolated skin lesions consists in surgical removal. 5 However, in up to 90% of cases, concomitant visceral metastases can be found, which explains why cutaneous metastases of RCC are associated with a poor prognosis, and a tumor--specific survival of less than six months.…”

Section: A B Cmentioning

confidence: 99%