2021
DOI: 10.1056/nejmc2033961
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Abstract: In 2019, we performed what we believe to be the first full-face transplantation in a Black patient. The patient was a 67-year-old man who had burns over 50% of his total body-

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Cited by 18 publications
(19 citation statements)
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“…Regarding cytomegalovirus (CMV) and Epstein-Barr virus (EBV) serologies, EBV status mismatch between FT recipient and donor served as an exclusion criterion for 2 programs (8%) 93,108 and CMV-positive donor/CMV-negative recipient (CMV D+/R−) mismatches were absolute exclusion criteria for 2 programs (8%) 108,115 . Nevertheless, FT has been performed on both CMV-positive and EBV-positive patients 54,93,106,108 . Four programs (17%) have performed FT in a CMV D+/R− pair, 41,45,69,79,80 with one of these programs later recommended against CMV D+/R− FTs 69 .…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Regarding cytomegalovirus (CMV) and Epstein-Barr virus (EBV) serologies, EBV status mismatch between FT recipient and donor served as an exclusion criterion for 2 programs (8%) 93,108 and CMV-positive donor/CMV-negative recipient (CMV D+/R−) mismatches were absolute exclusion criteria for 2 programs (8%) 108,115 . Nevertheless, FT has been performed on both CMV-positive and EBV-positive patients 54,93,106,108 . Four programs (17%) have performed FT in a CMV D+/R− pair, 41,45,69,79,80 with one of these programs later recommended against CMV D+/R− FTs 69 .…”
Section: Resultsmentioning
confidence: 99%
“…108,115 Nevertheless, FT has been performed on both CMV-positive and EBV-positive patients. 54,93,106,108 Four programs (17%) have performed FT in a CMV D +/R− pair, 41,45,69,79,80 with one of these programs later recommended against CMV D+/R− FTs. 69 For the remaining 16 centers, CMV or EBV status for either recipient or donor were not mentioned in their recipient criteria (67%).…”
Section: Pathologic/physiologic Considerationsmentioning
confidence: 99%
“…Accuracy of rejection detection on different skin colors, an important consideration for software-based image analysis of patients with FT, may be reduced on darker skin tones. 41 Despite our institution performing the first full-face transplant on a black patient, 42 we were unable to include his data due to having less than 2 years of follow-up data required by the study inclusion criteria. However, he remains one of two black patients with FT worldwide, highlighting the troubling duality racial disparities play in the field of transplantation [43][44][45] -decreased patient access leads to decreased information of patient outcomes.…”
Section: Future Directionsmentioning
confidence: 99%
“…3 Furthermore‚ the long-term survival of the allograft can be subject to acute and chronic graft rejection in solid organ transplantation (SOT) and vascularized composite allotransplantation (VCA), such as face, hand, penile, or abdominal wall transplants. 1,[4][5][6][7][8][9][10] Given the higher rate of diagnosed acute rejection episodes in up to 85% of VCA recipients, the link between long-term allograft survival and rejection episodes could theoretically even be more pronounced in VCA. 11 One approach to optimizing this risk-benefit ratio is the development of therapies allowing for safe reduction of immunosuppression.…”
Section: Introductionmentioning
confidence: 99%