Fabrication of Uniform Magnetic Nanocomposite Spheres with a Magnetic Core/Mesoporous Silica Shell Structure

Abstract

A novel kind of magnetic core/mesoporous silica shell nanospheres with a uniform particle diameter of ca. 270 nm was synthesized. The inner magnetic core endues the whole nanoparticle with magnetic properties, while the outer mesoporous silica shell shows high enough surface area and pore volume. The synthesized material is expected to be applied to targeted drug delivery and multiphase separation. The storage and release of ibuprofen into and from the pore channels of the mesoporous silica shell, as a typical example, are demonstrated.

Synthesis, characterization and magnetic properties of hematite (α-Fe2O3) nanoparticles on polysaccharide templates and their antibacterial activity

“…Such nanostructures are extensively used in magnetic materials, as photocatalyst, in sensors, medical applications such as hyperthermia, targeted drug delivery, magnetic resonance imaging, etc. (Zhao et al 2005). Choosing the right material for synthesis of iron oxide nanoparticles is crucial by varying the processing conditions with various forms of iron oxides such as Fe 3 O 4 , c-Fe 2 O 3 and a-Fe 2 O 3 .…”

Synthesis, Functionalization, and Design of Magnetic Nanoparticles for Theranostic Applications

“…Subsequently Fe 3 O 4 /Fe was produced by reducing the hematite cores in a flowing gas mixture of H 2 and N 2 . [353] In a very recent study, Kuzminska et al [354] reported thin and thick coating of Fe 3 O 4 MNPs with (3-aminopropyl)triethoxysilane and TEOS to increase their hydrophilicity and their pH stability. Their stability tests showed that coating with silica shell and grafting with organosilanes considerably improve the stability of MNP at pH = 3; the thicker the silica layer the less iron oxide dissolved.…”

Magnetically separable mesoporous Fe3O4/silica catalysts with very low Fe3O4 content

“…Different strategies have been explored to protect these NPs against agglomeration and oxidation [1][2][3][4][5][6][7][8][9], one of the most promising being the use of silica as protecting material due to its inertness and biocompatibility, featuring excellent stability and controllable surface chemistry and porosity [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Usually, the synthesis of Fe 3 O 4 /silica composites is based on the coating of a magnetic core (Fe 3 O 4 NPs) with a silica layer leading to core-shell morphologies [1][2][3][4][5][6][7][8][9]. We have recently reported the synthesis of uniform Fe 3 O 4 NPs with improved stability in acidic media, using the NPs as nuclei for the Stöeber synthesis of silica [2].…”