Fabrication of tragacanthin gum-carboxymethyl chitosan bio-nanocomposite wound dressing with silver-titanium nanoparticles using freeze-drying method

Liang, Huixing; Mirinejad, Maryam Sadat; Asefnejad, Azadeh; Baharifar, Hadi; Li, Xiang; Saber‐Samandari, Saeed; Toghraie, Davood; Khandan, Amirsalar

doi:10.1016/j.matchemphys.2022.125770

Cited by 85 publications

(10 citation statements)

References 56 publications

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“…Its natural form offers a complex and rich chemical structure with abundant active groups for sorption, and can easily be subjected to structural and electrical changes under facile pH variations. [29] To allow more practical use of mucin, however, its incorporation into a solid composite is required, similar to other biomaterials processed using different techniques such as 3D printing, [49] freeze-drying, [50,51] or electrospinning. [26] Specifically, mucin can be processed using green and environmentally-friendly methods into various shapes such as nanofibers (NFs), hydrogels, beads, films, and foams.…”

Section: Introductionmentioning

confidence: 99%

Mucin‐Based Composites for Efficient Mercuric Biosorption

Gavriely

Richter

Zucker

2022

Advanced Sustainable Systems

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In this study, the extraordinary biosorption of mucin, a natural glycoprotein with selectivity towards metals in physiological processes, is leveraged to remove heavy metals from wastewater. The authors assess the performance of dissolved mucin for Hg2+ adsorption through studies of kinetics, capacity, and selectivity. The results show that mucin can adsorb more than 124 mg g−1 Hg2+ while exhibiting ultra‐fast kinetics, with an equilibrium reached in a few seconds. The adsorption levels are optimized in pHs higher than 4 and remain almost unchanged in the presence of background ions. X‐ray photoelectron spectroscopy and Fourier transform infrared analyses indicated that the sorption mechanism is dominated by electrostatic interactions and mercuric complexation with mucin's active sites, whereas the undesirable removal via mercuric reduction does not occur. To use mucin in a practical and green fashion for metal adsorption, mucin‐based solid structures, including films, beads, and nanofibers (NFs), are fabricated and assessed. Of these structures, the NFs show the best performance, with an uptake over 109 mg g−1 and a high structural stability over multiple adsorption and regeneration cycles. The findings point to the potential use of mucin as a future green alternative for metal biosorption for environmental applications.

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Section: Introductionmentioning

confidence: 99%

Mucin‐Based Composites for Efficient Mercuric Biosorption

Gavriely

Richter

Zucker

2022

Advanced Sustainable Systems

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“…For wound dressing materials, bioadhesion behaviour is an important characteristic for their long time usage [50]. For this purpose, the effect of the CA amount in the Gel-MA/Pec-CA wound dressings on the bioadhesive properties was investigated.…”

Section: In Vitro Bioadhesion Assessmentmentioning

confidence: 99%

Assessment of Centella Asiatica Extract Containing Dual-crosslinked Gel-MA/Pec Hydrogels as Wound Dressing

ALBAYRAK>

GELAL>

Akalgan

et al. 2022

Hittite Journal of Science and Engineering

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In the present work, 3D-printed wound dressings containing different amounts of Centella Asiatica extract were synthesized via dual-crosslinking method. Methacrylic anhydride modified gelatin (Gel-MA) and pectin (Pec) were chosen as the base material for dressings. A dual crosslinked network was formed with Gel-MA photo-crosslinking using Irgacure 2959 and Pectin (Pec) psychical-crosslinking using Ca++ ions. Meanwhile, the developed dual-crosslinked hydrogel dressings were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, and mechanical, swelling, in vitro degradation as well as ex vivo bioadhesion tests. It has been observed that the preapred dressings provide good bioadhesion on the chicken skin. Moreover, MTT assay revealed cell viability of Gel-MA/Pec hydrogel dressings containing Centella Asiatica extract. The results presented the dressings as a promising biomaterial to be used for wound healing purposes, which should be further investigated in future.

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“…Synthetic polymers are almost as diverse as those found in nature, and new polymers have been quickly introduced into the medical field, such as polyester/polyamide synthetic sutures [ 19 , 20 ]. There are also functional types of polymers that have been developed for biomedical applications such as drug delivery devices, vascular stents, sutures, thrombectomy devices, aneurysm or ductus arteriosus closure, orthodontic therapy, and wound dressings [ 21 , 22 , 23 ]. The relative degradation rates and erosion mechanisms of hydrolytically degradable polymers are some of the key characteristics that significantly affect their ability to function as biomaterials [ 24 , 25 , 26 ].…”

Section: Introductionmentioning

confidence: 99%

A New Approach to Implant Stability Using a Flexible Synthetic Silicate-Additive Beta-Tricalcium Phosphate-Poly(D,L-lactide-co-caprolactone) Bone Graft: An In Vitro Study

Orhan,

Ciğerim

2024

Polymers

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The aim of this study was to evaluate the use of a flexible synthetic polymer bone graft to provide implant stability during implant placement in a dense cortical bone model. In the control group (Group 1), sockets were prepared on polyurethane blocks according to the standard implant socket drilling protocol; both oversizing and deepening were applied in Group 2; and only oversizing was applied in Group 3. In Groups 2 and 3, flexible synthetic polymer bone grafts were placed in the sockets prior to implant placement. The implants were placed at the bone level in all groups. The highest torque value obtained was recorded as the insertion torque. In this study, 75 implant sites were included across three groups. The torque values of the implants in the control group were significantly higher than those of the implants with the oversized and deepened sockets and the oversized-only sockets (p < 0.05; p < 0.01). The torque values of the implants with the oversized and deepened sockets were significantly higher than those of the implants with the oversized-only sockets (p < 0.01). In this study, a flexible synthetic polymer bone graft was shown to be effective in achieving implant stability in the management of implants where there has been a loss of primary stability.

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Fabrication of tragacanthin gum-carboxymethyl chitosan bio-nanocomposite wound dressing with silver-titanium nanoparticles using freeze-drying method

Cited by 85 publications

References 56 publications

Mucin‐Based Composites for Efficient Mercuric Biosorption

Mucin‐Based Composites for Efficient Mercuric Biosorption

Assessment of Centella Asiatica Extract Containing Dual-crosslinked Gel-MA/Pec Hydrogels as Wound Dressing

A New Approach to Implant Stability Using a Flexible Synthetic Silicate-Additive Beta-Tricalcium Phosphate-Poly(D,L-lactide-co-caprolactone) Bone Graft: An In Vitro Study

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