A reliable process has been developed for the fabrication of all-Nb single-electron circuits, based on spin-on glass planarization. The process steps are the in situ growth of Nb/AlO x /Nb sandwich, definition of the patterns of junctions, base electrodes and wiring by use of reactive ion etching and the planarization of a spin-on glass insulation between base electrode and wiring. A single electron transistor made of 0.3×0.3 µm 2 area junctions clearly shows the e-periodic Coulomb blockade modulation by a voltage applied to a gate.Up to now, Nb tunnel junctions have remained the most popular elements of superconductive electronics. Since the invention of the Nb/AlO x /Nb trilayer by Gurvich et al.1 , the fabrication of complex circuits of micrometerscale junctions has been well established. In the past years, there was a strong motivation to develop a technique for the reliable fabrication of Nb Josephson junctions of smaller sizes, characterized by smaller selfcapacitances, which are advantageous for application in both Josephson devices 2,3 and single electron circuits. Moreover, due to rather large values of the superconductor energy gap of Nb (∆ ≈ 1.4 meV) and, hence, larger Josephson-junction coupling, the small-capacitance Nb junctions are very promising for the single electron tunneling (SET) applications in which the interplay between the Coulomb charging energy E C and the Josephson coupling energy E J is realized 4 . A number of attempts were made to fabricate submicron-scale Nb/AlO x /Nb tunnel junctions. These approaches can be divided into two groups: first, the techniques in which the tunnel barrier was formed ex situ 5,6 , and, secondly, those in which it was grown in situ [7][8][9]