Fabrication of polymer lenses and microlens array for lab-on-a-chip devices

Olivieri, Federico; Todino, Michele; Coppola, Sara; Vespini, Veronica; Pagliarulo, Vito; Grilli, Simonetta; Ferraro, Pietro

doi:10.1117/1.oe.55.8.081319

Cited by 14 publications

(6 citation statements)

References 2 publications

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“…In recent years, microlens arrays have been widely used in the fields of optical sensing technology, laser beam shaping, artificial compound eye structures, optical fiber coupling, light-filed cameras, micro-manufacturing and lab-on-a-chip systems [1][2][3][4][5][6][7]. Micro lenson-lens arrays (MLLAs) with multiple focal lengths have great potential in the fields of real-time detection of unconfined or fluctuating targets, 3D reconstructions and imaging in multiple depth of fields [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

A Novel Fabricating Method of Micro Lens-on-Lens Arrays with Two Focal Lengths

Liu

Bian

et al. 2021

Micromachines

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Micro lens-on-lens array (MLLA) is a novel 3D structure with unique optical properties that cannot be fabricated accurately and quickly by existing processing methods. In this paper, a new fabricating method of MLLAs with two focal lengths is proposed. By introducing the soft lithography technology, nano-imprint technology and mask alignment exposure technology, MLLAs with high precisions can be obtained. A MLLA is successfully fabricated with two focal lengths of 58 μm and 344 μm, and an experiment is carried out. The results show that the MLLA has excellent two-level focusing and imaging abilities. Furthermore, the fabricated profiles of the MLLA agree well with the designed profiles, and the morphology deviation of the MLLA is better than 2%, satisfying the application requirements. The results verify the feasibility and validity of the novel fabricating method. By adjusting mask patterns and processing parameters, MLLAs with both changeable sizes and focal lengths can be obtained.

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Section: Introductionmentioning

confidence: 99%

A Novel Fabricating Method of Micro Lens-on-Lens Arrays with Two Focal Lengths

Liu

Bian

et al. 2021

Micromachines

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“…These applications require the fabrication of microlens arrays on different substrates or even on curved surfaces, thus requiring achievable microlens fabrication processes. Various methods for the fabrication of microlens array have been developed [5], including, but not limited to photoresist reflow method [6], hot embossing [7], and femtosecond laser direct-write [8]. However, conventional manufacturing processes are difficult to achieve large-scale microlens array fabrication on different substrates, or limited by expensive equipment and complicated processes.…”

Section: Introductionmentioning

confidence: 99%

Microlens Fabrication by Replica Molding of Electro-Hydrodynamic Printing Liquid Mold

et al. 2020

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In this paper, we synergistically combine electrohydrodynamic (EHD) printing and replica molding for the fabrication of microlenses. Glycerol solution microdroplets was sprayed onto the ITO glass to form liquid mold by an EHD printing process. The liquid mold is used as a master to fabricate a polydimethylsiloxane (PDMS) mold. Finally, the desired micro-optical device can be fabricated on any substrate using a PDMS soft lithography mold. We demonstrate our strategy by generating microlenses of photocurable polymers and by characterizing their optical properties. It is a new method to rapidly and cost-effectively fabricate molds with small diameters by exploiting the advantages of EHD printing, while maintaining the parallel nature of soft-lithography.

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“…The flexibility and transparency of this polymer also enables its use as a micro-electro-mechanical systems (MEMS) substrate or for microfluidic devices [ 29 , 30 , 31 ]. There are also some research about arrays of PDMS µ-lenses, proving the reproducibly of this material to replace the most conventional glass-based µ-lenses [ 32 , 33 ].…”

Section: Introductionmentioning

confidence: 99%

PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics

Costa

Pimenta

Ribeiro

et al. 2019

Sensors

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Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performance parameter is the light intensity at a given power consumption of the medical device. A method to increase the illumination intensity in the NBI diagnostic technique was developed and applied to minimally invasive medical devices (e.g., endoscopic capsules), without increasing the size and power consumption of such instruments. Endoscopic capsules are generally equipped with light-emitting diodes (LEDs) operating in the RGB (red, green, and blue) visible light spectrum. A polydimethylsiloxane (PDMS) µ-lens was designed for a maximum light intensity at the target area of interest when placed on top of the LEDs. The PDMS µ-lens was fabricated using a low-cost hanging droplet method. Experiments reveal an increased illumination intensity by a factor of 1.21 for both the blue and green LEDs and 1.18 for the red LED. These promising results can increase the resolution of NBI in endoscopic capsules, which can contribute to early gastric lesions diagnosis.

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Fabrication of polymer lenses and microlens array for lab-on-a-chip devices

Cited by 14 publications

References 2 publications

A Novel Fabricating Method of Micro Lens-on-Lens Arrays with Two Focal Lengths

A Novel Fabricating Method of Micro Lens-on-Lens Arrays with Two Focal Lengths

Microlens Fabrication by Replica Molding of Electro-Hydrodynamic Printing Liquid Mold

PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics

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