Fabrication of polycaprolactone/zirconia nanofiber scaffolds using electrospinning technique

Thakare, V. G.; Joshi, Pradyuman A.; Godse, R. R.; Bhatkar, V.B.; Wadegaokar, P. A.; Omanwar, S. K.

doi:10.1007/s10965-017-1388-z

Cited by 15 publications

(3 citation statements)

References 38 publications

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“…Several cell types, including fibroblasts and epithelial cells, have been reported to benefit from zirconium nanoparticles in terms of increased adhesion and proliferation. This may facilitate better soft tissue integration between the dental implant and the surrounding bone [ 93 ].…”

Section: Importance Of Zirconium Nanoparticlesmentioning

confidence: 99%

Advances of plant and biomass extracted zirconium nanoparticles in dental implant application

Hossain

Mobarak

Hossain

et al. 2023

Heliyon

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Section: Importance Of Zirconium Nanoparticlesmentioning

confidence: 99%

Advances of plant and biomass extracted zirconium nanoparticles in dental implant application

Hossain

Mobarak

Hossain

et al. 2023

Heliyon

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“…At 1470 and 1370 cm −1 , bands of moderate intensity were identified related to the axial deformation of aliphatic C-H groups and a 721 cm −1 out-ofplane CH deformation [18]. A PCL-0 sample showed the following typical polycaprolactone bands: a band in the range of 3637 to 3326 cm −1 , which can be attributed to the vibration of stretching and deformation of the hydroxyl groups (O-H) as a function of water absorption and coordination with the water [37]; at 2942 cm −1 , which can be referred to as the asymmetric stretching of the -CH2 group; at 2868 cm −1 , related to the symmetric stretching of the -CH2 A PCL-0 sample showed the following typical polycaprolactone bands: a band in the range of 3637 to 3326 cm −1 , which can be attributed to the vibration of stretching and deformation of the hydroxyl groups (O-H) as a function of water absorption and coordination with the water [37]; at 2942 cm −1 , which can be referred to as the asymmetric stretching of the -CH 2 group; at 2868 cm −1 , related to the symmetric stretching of the -CH 2 group; at 1726 cm −1 , due to the presence of the carbonyl ester group (C=O), with consequent stretching vibration of -CO [38]; at 1474 cm −1 , due to C-H vibration; at 1298 cm −1 , due to C-C and C-O stretching; at 1169 cm −1 , attributed to the asymmetric stretching of the C-O-C bond; and at 1040 cm −1 , due to C-O-C stretching vibration [39]. For sodium alginate (powder), bands were identified at 3378 cm −1 , representing the stretching vibration of the hydroxyl group O-H; at 2929 cm −1 , attributed to the symmetric stretching mode for CH 2 [40]; at 1610 cm −1 , referring to the COO-asymmetric stretch; at 1413 cm −1 , attributed to the C-OH group; at 1121 cm −1 , typical of the vibrations of the C-O/C-C groups; at 1087 cm −1 , related to the C-O-C cluster; and at 1026 cm −1 and 944 cm −1 , referring to the stretching of the C-O group, related to the residual mannuronic and guluronic acids in the composition of the alginate [41,42].…”

Section: Fourier Transform Infrared Spectroscopy (Ftir)mentioning

confidence: 99%

Poly (ε-caprolactone)-Based Scaffolds with Multizonal Architecture: Synthesis, Characterization, and In Vitro Tests

Lima,

Canelas,

Dutra

et al. 2023

Polymers

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Tissue engineering is vital in treating injuries and restoring damaged tissues, aiming to accelerate regeneration and optimize the complex healing process. In this study, multizonal scaffolds, designed to mimic tissues with bilayer architecture, were prepared using the rotary jet spinning technique (RJS scaffolds). Polycaprolactone and different concentrations of alginate hydrogel (2, 4, and 6% m/v) were used. The materials were swollen in pracaxi vegetable oil (PO) (Pentaclethra macroloba) and evaluated in terms of surface morphology, wettability, functional groups, thermal behavior, crystallinity, and cytotoxicity. X-ray diffraction (XRD) showed the disappearance of the diffraction peak 2θ = 31.5° for samples from the polycaprolactone/pracaxi/alginate (PCLOA) group, suggesting a reduction of crystallinity according to the presence of PO and semi-crystalline structure. Wettability gradients (0 to 80.91°) were observed according to the deposition layer and hydrogel content. Pore diameters varied between 9.27 μm and 37.57 μm. Molecular interactions with the constituents of the formulation were observed via infrared spectra with Fourier transform (FTIR), and their influence was detected in the reduction of the maximum degradation temperature within the groups of scaffolds (polycaprolactone/alginate (PCLA) and PCLOA) about the control. In vitro tests indicated reduced cell viability in the presence of alginate hydrogel and PO, respectively.

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“…The authors proposed an alternative approach for designing flexible zirconia scaffolds to traditional fragile ceramics for bone-tissue engineering. In a recent study, Thakare et al, focused on the engineering of PCL/zirconia composite nanofiber scaffolds by varying the amount of zirconia from 6% to 30% via the electrospinning process [98].…”

Section: Electrospinningmentioning

confidence: 99%

Three-Dimensional Zirconia-Based Scaffolds for Load-Bearing Bone-Regeneration Applications: Prospects and Challenges

et al. 2021

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The design of zirconia-based scaffolds using conventional techniques for bone-regeneration applications has been studied extensively. Similar to dental applications, the use of three-dimensional (3D) zirconia-based ceramics for bone tissue engineering (BTE) has recently attracted considerable attention because of their high mechanical strength and biocompatibility. However, techniques to fabricate zirconia-based scaffolds for bone regeneration are in a stage of infancy. Hence, the biological activities of zirconia-based ceramics for bone-regeneration applications have not been fully investigated, in contrast to the well-established calcium phosphate-based ceramics for bone-regeneration applications. This paper outlines recent research developments and challenges concerning numerous three-dimensional (3D) zirconia-based scaffolds and reviews the associated fundamental fabrication techniques, key 3D fabrication developments and practical encounters to identify the optimal 3D fabrication technique for obtaining 3D zirconia-based scaffolds suitable for real-world applications. This review mainly summarized the articles that focused on in vitro and in vivo studies along with the fundamental mechanical characterizations on the 3D zirconia-based scaffolds.

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Fabrication of polycaprolactone/zirconia nanofiber scaffolds using electrospinning technique

Cited by 15 publications

References 38 publications

Advances of plant and biomass extracted zirconium nanoparticles in dental implant application

Advances of plant and biomass extracted zirconium nanoparticles in dental implant application

Poly (ε-caprolactone)-Based Scaffolds with Multizonal Architecture: Synthesis, Characterization, and In Vitro Tests

Three-Dimensional Zirconia-Based Scaffolds for Load-Bearing Bone-Regeneration Applications: Prospects and Challenges

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