Advances of plant and biomass extracted zirconium nanoparticles in dental implant application

Hossain, Nayem; Mobarak, Md Hosne; Hossain, Amran; Khan, Fardin; Mim, Juhi Jannat; Chowdhury, Mohammad Asaduzzaman

doi:10.1016/j.heliyon.2023.e15973

Cited by 30 publications

(9 citation statements)

References 115 publications

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“…It can result in peri-implant bone resorption, distortion of the impression, improper fit of removable or fixed prostheses, fracture of implant screws or porcelain prosthetic crowns, and chewing pain by altering the distribution of masticatory stresses and increasing their intensity in implant-supported prostheses, abutments, and surrounding bone [ 94 ]. Consequently, it is essential to implement therapeutic modifications and preventive measures to reduce the negative effects of this phenomenon on oral rehabilitations [ 23 , 27 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 ].…”

Section: Discussionmentioning

confidence: 99%

Biomechanical Implications of Mandibular Flexion on Implant-Supported Full-Arch Rehabilitations: A Systematic Literature Review

Caggiano,

D’Ambrosio,

Acerra

et al. 2023

JCM

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Background: Mandibular flexion (MF) is a complex biomechanical phenomenon, which involves a deformation of the mandible, due mainly to the contraction of the masticatory muscles, and it can have numerous clinical effects. The deformation of the lower jaw caused by mandibular flexion is generally very small, and it is often overlooked and considered irrelevant from a clinical point of view by many authors; however, it should be important to remember that median mandibular flexure (MMF) has a multifactorial aetiology. The main aim of the current systematic review is to highlight the different factors that can increase MF in order to help clinicians identify patients to whom they should pay more attention. As a secondary outcome, we wanted to analyse the preventive measures and suitable techniques to be adopted to minimise the negative effects of this phenomenon on oral fixed rehabilitations. Methods: The review, which was carried out in accordance with the “Preferred Reporting Items for Systematic reviews and Meta-Analyses” (PRISMA) flowchart, was recorded in the “International Prospective Register of Systematic Reviews” (PROSPERO). As research questions, “Patient/Population, Intervention, Comparison and Outcomes” (PICO) questions were employed. Using the ROBINS-I technique, the risk of bias in non-randomised clinical studies was evaluated. Results: The initial electronic search identified over 1300 potential articles, of which 54 studies were included in this systematic review. Information regarding the relationship between MF and individual factors, mandibular movements, impression taking, and fixed rehabilitations were obtained. Conclusions: The studies included in this systematic review showed that MF is greater during protrusive movements, in the posterior areas of the lower jaw, and in patients with brachial facial type, greater jaw length; small gonial angle; and less density, length, and bone surface of the symphysis. The biomechanical effects of mandibular flexion on fixed restorations are debated. Prospective clinical and radiological observational studies should be conducted to evaluate the potential short-, medium-, and long-term consequences of MF.

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Section: Discussionmentioning

confidence: 99%

Biomechanical Implications of Mandibular Flexion on Implant-Supported Full-Arch Rehabilitations: A Systematic Literature Review

Caggiano,

D’Ambrosio,

Acerra

et al. 2023

JCM

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Section: Description Of the Advantages And Limitations Of Using Zro 2...mentioning

confidence: 99%

“…It is a challenge, and more investigations are required to compare their behavior to other biomaterials used in the dental field and find the best safe usage conditions. As an example, Zirconium nanoparticles have no standard for production leading to specific characteristics and functionality and such things should be solved [128,205,206]. This review highlights the potential of ZrO 2 nanostructures as drug delivery vehicles and the progress that has been made in understanding their properties, drug loading and release mechanisms, biocompatibility, and toxicity.…”

Section: Description Of the Advantages And Limitations Of Using Zro 2...mentioning

confidence: 99%

Present and Future of ZrO2 Nanostructure as Reservoir for Drug Loading and Release

Radu

Drăgănescu

2023

Coatings

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Extensive research has been conducted on ZrO2 nanostructures due to their favorable biocompatibility, low toxicity, and promising prospects in various biomedical applications. They can be used as drug carriers, facilitating the administration of therapeutic substances into the body while enhancing their effectiveness and safety. This is achieved by regulating the timing, location, and rate at which drugs are released within the body. Several factors can influence the effectiveness of drug loading onto ZrO2 nanostructures, such as the physicochemical characteristics of the drugs, the surface properties of the ZrO2 nanostructures, and the specific methods used for drug loading. A wide range of drugs may be loaded onto ZrO2 nanostructures including anti-cancer drugs, antibiotics, anti-inflammatory drugs, antifungal drugs, anti-osteoporotic drugs, etc. The release kinetics of drugs can be influenced by different factors, such as the size and shape of ZrO2 nanostructures, the pH and temperature of the release medium, and the characteristics and molecular weight of the specific drug being released. While ZrO2 nanostructures have demonstrated significant potential as drug delivery systems, further research on these structures is essential to optimize drug loading and release strategies.

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“…Gelatin is versatile in its processing and has promise biocompatibility and biodegradability [ 13 ]. Zirconium oxide (ZrO 2 ) is a extensive group breach (5.0–5.5 eV), thermally stable, chemically inert, and non-toxic transition metal oxide [ 14 ]. ZrO 2 creates a strong covalent bond (Zr–O), which makes the monoclinic structure durable at moderate temperatures, especially room temperature [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of novel nanofiber composed of gelatin/alginate with zirconium oxide NPs regulate orthodontic progression of cartilage degeneration on Wnt/β-catenin signaling axis in MC3T3-E1 cells

Zhao

2024

Regenerative Therapy

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Advances of plant and biomass extracted zirconium nanoparticles in dental implant application

Cited by 30 publications

References 115 publications

Biomechanical Implications of Mandibular Flexion on Implant-Supported Full-Arch Rehabilitations: A Systematic Literature Review

Biomechanical Implications of Mandibular Flexion on Implant-Supported Full-Arch Rehabilitations: A Systematic Literature Review

Present and Future of ZrO2 Nanostructure as Reservoir for Drug Loading and Release

Fabrication of novel nanofiber composed of gelatin/alginate with zirconium oxide NPs regulate orthodontic progression of cartilage degeneration on Wnt/β-catenin signaling axis in MC3T3-E1 cells

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