2009
DOI: 10.1016/j.actbio.2009.01.007
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Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells

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Cited by 242 publications
(210 citation statements)
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“…Enhancement of cell adhesion by various nanotextures or micro/nanotextures has been widely reported. 16,23,[31][32][33] However, the exact effect of nanotextures on cell adhesion activity remains to be determined. 34 One possible explanation is that the high surface energy of the sharp ridges in the nanoscale range facilitates formation of focal adhesions.…”
Section: Cell Adhesion Activitymentioning
confidence: 99%
“…Enhancement of cell adhesion by various nanotextures or micro/nanotextures has been widely reported. 16,23,[31][32][33] However, the exact effect of nanotextures on cell adhesion activity remains to be determined. 34 One possible explanation is that the high surface energy of the sharp ridges in the nanoscale range facilitates formation of focal adhesions.…”
Section: Cell Adhesion Activitymentioning
confidence: 99%
“…However, a small drawback is its bioinert nature [3]. To overcome this, possible strategies are to optimize the topography or to mix it with another material that can activate cell growth [4]. Silicon oxide supports cell growth and hence can be used as the other phase in the mixture [5].…”
Section: Introductionmentioning
confidence: 99%
“…For example, by creating nano-sized features on titanium-based surfaces the expression of bone sialoprotein (BSP) and osteopontin was stimulated by osteogenic cells (2). The enhancement of osteoblast adhesion and function on different nanostructured metal and ceramic materials was demonstrated in further studies (3,4).…”
Section: Introductionmentioning
confidence: 99%