Open air plasma deposited antimicrobial SiO_x/TiO_x composite films for biomedical applications

Abstract

Open air atmospheric pressure plasma jet (APPJ) enhanced chemical vapour deposition process was used to deposit biocompatible SiO x /TiO x composite coatings. The as deposited films are hydrophilic and show visible light induced photocatalytic effect, which is a consequence of the formation of defects in the TiO x structure due to the plasma process. This photocatalytic effect was verified by the demonstration of an antimicrobial effect under visible light on E. coli as well as by degradation of Rhodamine B. The films are non-cytotoxic as shown by the cytocompatibility tests. The films are conductive to cell growth and are stable in DMEM and isopropanol. The structural evaluation using SEM, EDS and XPS shows a dispersion of TiO x phase in a SiO x CyHz matrix. These analyses were used to correlate the structure-property relationship of the composite coating.

Effects of nanopillars and surface coating on dynamic traction force

“…In addition, the surface chemistry of biomaterials, such as wettability, is known to influence cell responses. Hydrophilic silicon oxide and titanium oxide are often used as coatings for implanted devices due to their good biocompatibility 20 , 21 . Surface energy of the ECM can control fluid interactions, cell adhesion, and protein adsorption, thus influencing tissue formation 22 .…”

Atmospheric plasma deposition of conductive and corrosion‐resistant composite coatings for proton exchange membrane fuel cell bipolar plates

“…Most atmospheric pressure plasma approaches involved an aerosol-assisted strategy in which a liquid suspension of the fillers and the matrix precursors is atomized and injected in the form of an aerosol in the plasma discharge [14,16,[18][19][20][21] or postdischarge. [22,23] The aerosol-assisted plasma deposition enabled to embed a wide range of fillers (e.g., metal nanoparticles, [16,22] oxide nanoparticles, [20,23] or enzymes [19,21] ) in a variety of matrix compositions (e.g., plasma-polymerized hexamethyldisiloxane, [16,20] alkenes, [19,21] or pyrrole [19] ). On the other hand, the plasma curing of liquid layers has also enabled the embedment of various fillers (cyclodextrines, [24] metalloporphyrins, [25,26] coordination polymers nanoparticles, [15] TiO 2 and CeO 2 nanoparticles [27] ) for sensing [24,25] or optical applications.…”

Effects of Nanopillars and Surface Coating on Dynamic Traction Force

“…The hydrophilic silicon oxide and titanium oxide are often used as coatings for implanted devices due to their good biocompatibility. 20,21 Surface energy on ECM can control uid interaction, cell adhesion, and protein adsorption, thus in uences tissue formation. 22 It had been reported that surface with a contact angle of ~ 70° provided the best control of cell behaviors.…”