Fabrication of Nano‐CuO@ZnO for the Synthesis of Functionalized β‐Enaminone Derivatives from β‐Nitrostyrenes, Aliphatic/Aromatic Amines and 1,3‐Dicarbonyl/4‐Hydroxy Coumarin

Abstract

Here, we have reported synthesis, characterization of CuO doped ZnO nanoparticles (CuO@ZnO NPs) and its applications for the synthesis of functionalized β‐enaminone derivatives via one‐pot three component reactions of β‐nitrostyrenes, aliphatic/aromatic amines or alcohols and 5,5‐dimethylcyclohexane‐1,3‐dione/4‐hydroxycoumarin. The present CuO@ZnO NPs‐catalyzed sustainable protocol has enabled access to variety of β‐enaminone derivatives in moderate to excellent yields (61‐96%) in comparatively short reaction time periods (2‐3 h). The catalyst was found to be very stable under the reaction conditions and easily recovered from reaction mixture by filtration and recycled for at least ten times without significant loss in its catalytic efficiency.

Structural tuning enables piezochromic and photochemical properties in N-aryl-β-enaminones

“…While they can be readily prepared by either condensation 7 of dimedone, orthoester, and aniline or dehydration 8 of 3-acetyl-4hydroxycoumarin and arylamine, the scope of these reactions is rather limited. Recently, Banerjee 9 and coworkers reported a highly atom-economical and efficient method for the preparation of N-aryl-b-enaminones via CuO-ZnO NPs-catalyzed, onepot three-component reaction of 4-hydroxycoumarin/ dimedone, b-nitrostyrene, and arylamine. Nevertheless, the CuO-doped ZnO nanoparticles are currently not commercially available, and the self-prepared nanomaterials need to be analyzed by sophisticated spectroscopic and analytical techniques.…”