Fabrication of Efficient and Non-Enzymatic Electrochemical Sensors for the Detection of Sucrose

Abstract

Molecularly imprinted polymers have been used for the creation of an electrochemical sensor for the detection of sucrose, which are modified by using functionalized graphene (fG). Using AIBN as the free radical initiator and sucrose as the template, imprinted polymers are synthesized. The monomer, 4,4′-diisocyanatodiphenylmethane (DPDI), has both proton donor groups (N-H or O-H) and lone-pair donor groups (C=O). By creating H-bonds with electron donor groups (C=O), the proton donor group in this polymer may interact with the sugar molecule serving as its template. The sensor signals have improved as a result of the interaction between the monomer and the template. Thermogravimetric and differential thermal analysis (TGA/DTA) curves, scanning electron microscopy (SEM), and FT-IR spectroscopy have been employed to characterize the fabricated receptors. The fabricated sensor has exhibited a limit of detection of 16 ppb for the target analyte that is highly sensitive, linear, reversible, regenerative, and selective. Moreover, the sensor’s stability, reproducibility, and reusability have been evaluated for six months, following the device’s manufacturing, and the results revealed similar responses with the percentage error of less than 1%. Most importantly, this sensor has demonstrated a quick response time, which is very sensitive, stable, and selective.

A simple and ultra‐sensitive electrochemical sensing approach for detection of arsenic (v) in drinking water

“…Moreover, morphological study of imprinted polymer features shows the formation of distinct cavities by template molecules. These observations are good in agreement with previous reports [35–37] that increased roughness of composite layers increases surface area and facilitates adsorption of template molecules. For the determination of sensor efficiency and electrode processing, surface rough is an important parameter.…”

“…These imprints contain template specific recognition binding properties. Generation of MIPs is based on the process in which analyte, monomer and cross-linker are polymerized together through reversible covalent, non-covalent and semi-covalent interactions [35]. In the present work, an ion imprinted polymer (IIP) was designed for Arsenic (v) determination in water showing remarkable sensitivity and selectivity with interdigital electrode (IDE) as transducer.…”

A Sequential Electrospinning of a Coaxial and Blending Process for Creating Double-Layer Hybrid Films to Sense Glucose

“…By HSL conversion of the response color of 1–15 mmol/L, the color phase angle of each color was obtained, and its angle value was linearly fit, yielding R 2 = 0.96707 ( Figure 9 c), which already includes the human blood glucose concentration range (3.9–6.1 mmol/L), meeting the needs for simple testing of human blood glucose. Today, new kinds of polymers [ 80 , 81 , 89 ], organic and inorganic nanoparticles [ 90 , 91 ], and novel strategies for biomedical applications [ 92 , 93 , 94 , 95 , 96 , 97 ] are continuously reported. These achievements can be borrowed into the design and development of electrospun nanofibers, and thus promote new kinds of sensors and biomedical devices.…”