Fabrication of an Au-doped Cu/Fe oxide-polymer core–shell nanoreactor with chemodynamic and photodynamic dual effects as potential cancer therapeutic agents
Abstract:Nanoparticles are widely used in biomedical applications and cancer treatments due to their minute scale, multi-function, and long retention time. Among the various nanoparticles, the unique optical property derived from the localized surface plasmon resonance effect of metallic nanoparticles is a primary reason that metallic nanoparticles are researched and applied. Copper and Iron nanoparticles have the potential to generate hydroxyl radicals in excess H2O2 via Fenton or Fenton-like reactions. On the other h… Show more
The anticancer efficacy of chemodynamic therapy (CDT) is significantly reduced due to the mild acidic nature of the tumour microenvironment (TME). Typically, Fenton catalysts require a strong acidic microenvironment for...
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