Fabrication of alumina ceramics with functional gradient structures by digital light processing 3D printing technology

Zeng, Yong; Sun, Lijun; Yao, Haihua; Chen, Jimin

doi:10.1016/j.ceramint.2021.12.275

Cited by 30 publications

(5 citation statements)

References 33 publications

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“…2b. Following the standard PDF card, alumina material with good crystallinity displays X-ray diffraction characteristic peaks at approximately 25.58, 35.15, 37.78, 43.36, and 57.50 degrees (30). The statistical analysis indicates that the characteristic peaks of the sintered parts align with those speci ed in the standard PDF card.…”

Section: Analysis Of Scaffold Compositionmentioning

confidence: 90%

3D Printed Triply Periodic Minimal Surface Ceramic Scaffold Loaded with Bone Morphogenetic Proteins-2 and Zoledronic for Cranium Defect repairment

Yan,

Qi,

Zhao

et al. 2024

Preprint

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Managing large, critical-sized bone defects poses a complex challenge, especially when autografts are impractical due to their size and limited availability. In such situations, the development of synthetic bone implants becomes crucial. These implants can be carefully designed and manufactured as potential bone substitutes, offering controlled parameters such as porosity, hardness, and osteogenic cues. In this study, we employed digital light processing (DLP) technology to construct an alumina ceramic scaffold featuring a triply periodic minimal surface (TPMS) structure for bone transplantation. The scaffold was filled with type I collagen to enhance cell infiltration, thereby increasing the total surface area. Furthermore, the scaffold was functionalized with type I collagen, serving as a carrier for bone morphogenetic proteins-2 (BMP-2) and zoledronic acid (ZA). Using a clinically relevant rabbit cranium defect model, the scaffold underwent in vitro biocompatibility testing and in vivo assessment for its functionality in repairing critical-sized bone defect (approximately 8 mm). Our animal-based study results revealed that the Gyroid scaffold, functionalized with bioactive molecules, provided a conductive surface for promoting increased bone formation and enhancing the healing process in critical-sized long bone and cranium defects. These findings offer preclinical evidence supporting the use of a triply periodic minimal surface structure composite scaffold and present compelling support for its application as an advanced synthetic bone substitute in the future.

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Section: Analysis Of Scaffold Compositionmentioning

confidence: 90%

3D Printed Triply Periodic Minimal Surface Ceramic Scaffold Loaded with Bone Morphogenetic Proteins-2 and Zoledronic for Cranium Defect repairment

Yan,

Qi,

Zhao

et al. 2024

Preprint

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“…The process of preparing porous ceramics by additive manufacturing includes material spraying, material extrusion, reduction photopolymerization, adhesive spraying, SLS, and so on. This method has the advantages of fast speed, wide application, less energy consumption, and controllable pore structure, but the prepared ceramic material has the disadvantages of low strength, easy deformation, and cracking when sintered 129,168,169,171 …”

Section: Preparation Methods Of Bionic Ceramicsmentioning

confidence: 99%

“…This method has the advantages of fast speed, wide application, less energy consumption, and controllable pore structure, but the prepared ceramic material has the disadvantages of low strength, easy deformation, and cracking when sintered. 129,168,169,171 In general, the copy template method, freeze casting, gel casting, and sol-gel method can be used to prepare open porous ceramics. Methods such as pore forming agents and direct foaming can be used to prepare closed porous ceramics.…”

Section: Other Methodsmentioning

confidence: 99%

Research and application of biomimetic modified ceramics and ceramic composites: A review

Li,

Guo,

Huang

et al. 2023

J Am Ceram Soc.

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Ceramic materials are widely used in engineering field because of their good physical and chemical properties. The poor mechanical properties of traditional ceramics seriously limit the development of ceramic materials and have attracted extensive attention since its birth. The development of high toughness, light weight, and functional ceramic materials has long been the pursuit of materials scientists. Since ancient times, nature has been the source of all kinds of human technological ideas, engineering principles, and major inventions. The functional structure of biology provides a good research object for the bionic design and preparation of ceramic materials. Therefore, it is necessary to summarize the functional structures and mechanisms in nature and biomimetic preparation technology. The purpose of this review is to provide guidance for the functionalized biomimetic design and efficient preparation of ceramic materials. Some typical functional examples in nature are introduced in detail, and several representative biomimetic preparation methods are listed. Finally, the performance and application status of biomimetic ceramics are summarized, and the future development direction of biomimetic ceramic materials is prospected.

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“…The consolidation of the ceramic particles in the 3D structure is usually enabled via thermal sintering at temperatures exceeding 1000 °C, which is nowadays a widely accepted method to ensure suitable mechanical properties of the final ceramic bodies. 23 Although enormous progress in 3D printing of non-porous materials such as alumina, 13,24,25 titania 26 and zirconia 27,28 has been made in the recent five years, the same approach is not applicable to obtain porous pellets relevant for catalysis, because thermal sintering destroys the internal porosity of the catalyst material, reducing dramatically the specific surface area. 29 Pyrolysis at a lower temperature is an option that preserves the catalyst porosity; 30 however, the presence of carbon deposits on the final structure can be detrimental for catalytic applications.…”

Section: Catalysis Science and Technology Papermentioning

confidence: 99%

Towards unconstrained catalyst shaping: high accuracy DLP printing of porous γ-Al₂O₃-based catalysts

Mastroianni,

Russo,

Eränen

et al. 2024

Catal. Sci. Technol.

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Fabrication of alumina ceramics with functional gradient structures by digital light processing 3D printing technology

Cited by 30 publications

References 33 publications

3D Printed Triply Periodic Minimal Surface Ceramic Scaffold Loaded with Bone Morphogenetic Proteins-2 and Zoledronic for Cranium Defect repairment

3D Printed Triply Periodic Minimal Surface Ceramic Scaffold Loaded with Bone Morphogenetic Proteins-2 and Zoledronic for Cranium Defect repairment

Research and application of biomimetic modified ceramics and ceramic composites: A review

Towards unconstrained catalyst shaping: high accuracy DLP printing of porous γ-Al₂O₃-based catalysts

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Fabrication of alumina ceramics with functional gradient structures by digital light processing 3D printing technology

Cited by 30 publications

References 33 publications

3D Printed Triply Periodic Minimal Surface Ceramic Scaffold Loaded with Bone Morphogenetic Proteins-2 and Zoledronic for Cranium Defect repairment

3D Printed Triply Periodic Minimal Surface Ceramic Scaffold Loaded with Bone Morphogenetic Proteins-2 and Zoledronic for Cranium Defect repairment

Research and application of biomimetic modified ceramics and ceramic composites: A review

Towards unconstrained catalyst shaping: high accuracy DLP printing of porous γ-Al2O3-based catalysts

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Towards unconstrained catalyst shaping: high accuracy DLP printing of porous γ-Al₂O₃-based catalysts