Fabrication of a sensor for simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified carbon nanotube paste electrode

Akhgar, Mohammad Reza; Beitollahi, Hadi; Salari, Mohammad; Karimi-Maleh, Hassan; Zamani, Hassan Ali

doi:10.1039/c1ay05503h

Cited by 86 publications

(25 citation statements)

References 32 publications

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“…DA, AC and Trp are categorized as nitrogen aromatic compounds, which they possess similar chemical structure and properties. In addition, AC and Trp have influence on the synthesis of the neurotransmitter serotonin, because AC affects Trp metabolism so that it can increase the availability of Trp for generating serotonin [29,30]. Therefore, our research focuses on the development of electrodes for simultaneous electrochemical detection of DA, AC and Trp.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical preparation of nickel and copper oxides-decorated graphene composite for simultaneous determination of dopamine, acetaminophen and tryptophan

Liu

Ouyang

Ding

et al. 2016

Talanta

185

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Section: Introductionmentioning

confidence: 99%

Electrochemical preparation of nickel and copper oxides-decorated graphene composite for simultaneous determination of dopamine, acetaminophen and tryptophan

Liu

Ouyang

Ding

et al. 2016

Talanta

185

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“…It has been proved that electrochemical methods, compared with other methods, are very simple, sensitive, cost‐effective and rapid. These methods are advantageous for the determination of organic compounds that are involved in redox reactions such as medicines, various chemical compounds and specific moieties in biological fluids …”

Section: Introductionmentioning

confidence: 99%

Application of a nanostructured sensor based on graphene‐ and ethyl 2‐(4‐ferrocenyl[1,2,3]triazol‐1‐yl)acetate‐modified carbon paste electrode for determination of methyldopa in the presence of phenylephrine and guaifenesin

Beitollahi

Movlaee

Ganjali

et al. 2018

Applied Organom Chemis

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We introduce a new method to determine methyldopa without the interference of phenylephrine and guaifenesin. For this purpose, a carbon paste electrode was modified with graphene and ethyl 2-(4-ferrocenyl[1,2,3]triazol-1-yl)acetate. According to electrochemical studies, oxidation current of methyldopa on the surface of the modified electrode increased and shifted towards negative potentials. This modified electrode demonstrated two linear ranges of 0.4-30.0 μM and 30.0-500.0 μM with a detection limit of 0.08 μM. No change was observed in the sensitivity of the modified electrode towards methyldopa in the presence of phenylephrine and guaifenesin, which enables the simultaneous or independent measurement of the three moieties. The efficiency of the proposed modified electrode was evaluated through the determination of these substances in real samples.

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“…1, 2013 of research articles published in recent years report many remarkable claims about the advantages of carbon nanotubes, such as increased voltammetric currents, [23][24][25] increased heterogeneous electron-transfer rates, 26 insignificant surface fouling of CNT-based electrodes, 27,28 and an apparent "electrocatalytic" effect towards the redox process of a wide variety of compounds. [29][30][31][32][33] In this study, it was described initially the application of 3,4-dihydroxycinnamic acid as a suitable mediator in the electrocatalysis and voltammetric determination of CA in an aqueous buffer solution. In sequence, in order to demonstrate the catalytic ability of the modified electrode in the electrooxidation of CA in real samples, the method was employed for the voltammetric determination of CA in urine samples from both patients in CA treatment and healthy subjects and on medicines.…”

Section: Introductionmentioning

confidence: 99%

Electrocatalytic determination of cysteamine using multiwall carbon nanotube paste electrode in the presence of 3,4-dihydroxycinnamic acid as a homogeneous mediator

Keyvanfard¹,

Sami²,

Karimi-Maleh³

et al. 2013

J. Braz. Chem. Soc.

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A eletrooxidação da cisteamina (CA) foi estudada por eletrodos de pasta de nanotubos de carbono modificados com ácido 3,4-diidroxicinâmico (3,4-DHCA) usando voltametria cíclica, cronoamperometria e voltametria de varredura linear. Usando o eletrodo modificado, a cinética de eletrooxidação da CA foi consideravelmente intensificada através da redução do potencial anódico por meio de uma reação catalítica. O mecanismo de comportamento eletroquímico da CA na superfície do eletrodo modificado foi analisado por vários métodos eletroquímicos, na presença de mediador. O eletrodo modificado preparado apresentou respostas voltamétricas com alta sensibilidade para CA, o que o torna muito adequado para a detecção de CA em quantidades de traço. Um intervalo dinâmico linear de 0,25-400 µmol L −1 para a CA foi obtida em solução tamponada com pH 7,0. O limite de detecção foi de 0,09 µmol L −1 .The electrooxidation of cysteamine (CA) was studied by modified carbon nanotubes paste electrode in the presence of 3,4-dihydroxycinnamic acid (3,4-DHCA) using cyclic voltammetry, chronoamperometry and linear sweep voltammetry. Using the modified electrode, the kinetics of CA electrooxidation was considerably enhanced by lowering the anodic over-potential through a catalytic fashion. The mechanism of CA electrochemical behavior at the modified electrode surface was analyzed by various electrochemical methods in the presence of mediator. The prepared modified electrode showed voltammetric responses with high sensitivity for CA, making it very suitable for the detection of CA at trace levels. A linear dynamic range of 0.25-400 µmol L −1 for CA was obtained in buffered solutions with pH 7.0. The limit of detection was 0.09 µmol L −1 . Keywords: cysteamine, electrocatalysis, voltammetry, multiwall carbon nanotubes, 3,4-dihydroxycinnamic acid IntroductionCysteamine is an important thiol drug for the treatment of cystinosis.1 The deficiency of a cystine carrier in the lysosomal membrane leads to cystine accumulation within the lysosomes, ultimately crystallizing in vital organs such as the liver, kidney, spleen, intestines, and cornea.2,3 A number of long term clinical trials have shown that cysteamine administration (as cysteamine hydrochloride) stabilizes renal function, delays glomerular deterioration and improves linear growth. 4 Cysteamine and its disulfide, cystamine, have been shown to be neuroprotective in a number of cell culture and animal models.5 With this goal in mind, a rapid but specific and sufficiently sensitive analytical method was required for total cysteamine determination in biological and pharmaceutical samples. Numerous methods have been reported for the determination of CA in pharmaceutical and biological samples including chromatography, 6-8 electrophoresis, 9 gas chromatography with flame photometric detection, 10 ion exchange chromatography, 11 and electrochemical methods 12-14 using modified electrodes. Due to problems in chromatographic methods such as selecting a suitable column or a mobile phase with liquid chrom...

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Fabrication of a sensor for simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified carbon nanotube paste electrode

Cited by 86 publications

References 32 publications

Electrochemical preparation of nickel and copper oxides-decorated graphene composite for simultaneous determination of dopamine, acetaminophen and tryptophan

Electrochemical preparation of nickel and copper oxides-decorated graphene composite for simultaneous determination of dopamine, acetaminophen and tryptophan

Application of a nanostructured sensor based on graphene‐ and ethyl 2‐(4‐ferrocenyl[1,2,3]triazol‐1‐yl)acetate‐modified carbon paste electrode for determination of methyldopa in the presence of phenylephrine and guaifenesin

Electrocatalytic determination of cysteamine using multiwall carbon nanotube paste electrode in the presence of 3,4-dihydroxycinnamic acid as a homogeneous mediator

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