Fabrication, Modeling and Characterization of Magnetostrictive Short Fiber Composites

Wang, Zhenjin; Mori, Kazuki; Nakajima, Kenya; Narita, Fumio

doi:10.3390/ma13071494

Cited by 24 publications

(14 citation statements)

References 21 publications

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“…Tahap optimasi geometri senyawa Andrographolide dan Dendronpholide G dilakukan dengan menggunakan software HyperChem Professional 8.0. Optimasi geometri ini bertujuan untuk memperoleh konfirmasi stuktur yang sebenarnya dengan metode semi empiris AM1 (Wang et al, 2020).…”

Section: Optimasi Geometri Senyawa Ujiunclassified

UJI AKTIVITAS ANTIKANKER PAYUDARA SENYAWA ANDROGRAFOLIDA DARI TUMBUHAN SAMBILOTO (Andrographis paniculata (Burm F) Ness.) TERHADAP HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER-2) SECARA IN SILICO

Suherlan

Rohayah

Fakih

2021

JIFF

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Kanker payudara merupakan suatu keadaan dimana sel telah kehilangan pengendalian dan mekanisme normalnya, sehingga terjadi pertumbuhan yang tidak normal, cepat, dan tidak terkendali pada jaringan payudara. Kanker payudara dapat menyebabkan kematian pada kaum wanita. Andrographolide merupakan salah satu senyawa antikanker yang terkandung pada tanaman sambiloto (Andrographis Paniculata (Burm F) Ness.). Adapun reseptor Human Epidermal Growth Factor Receptor 2 (HER-2) merupakan resepor yang memiliki peranan penting pada kanker payudara. Tujuan pada peneitian ini adalah untuk mengetahui afinitas dan interaksi antara senyawa Andrographolide dan Dendronpholide G dengan reseptor HER-2 secara in silico. Pada penelitian ini dilakukan identifikasi sifat fisikokimia senyawa Andrographolide dan Dendronpholide G dengan menggunakan server swiss-ADME. Kemudian senyawa tersebut dioptimasi menggunakan software Avogadro. Setelah mendapatkan konformasi senyawa uji terbaik kemudian dilakukan tahap selanjutnya yaitu simulasi molecular docking menggunakan reseptor HER-2 terhadap senyawa uji menggunakan software MGL Tools 1.5.6 yang dilengkapi Autodock Tools 4.2. Adapun hasil penelitian yang diperoleh yaitu interaksi yang terjadi pada senyawa uji Andrographolide menghasilkan energi bebas ikatan sebesar −5,42 Kcal/mol dan nilai konstanta inhibisi 105,72 nM, sedangkan Dendranpholide G menghasilkan energi bebas ikatan sebesar −3,67 Kcal/mol dan nilai konstanta inhibisi 2,05 µM. Interaksi pada senyawa Andrographolide dan Dendranpholide G dengan reseptor HER-2 yaitu 1 ikatan hidrogen (MET801) dan terdapat 4 interaksi hidrofobik (MET801, LEU726, ALA751, LEU852). Hasil dari simulasi molecular docking dapat diprediksi bahwa senyawa Andrographolide memiliki afinitas yang baik dibandingkan senyawa Dendranpholide G maka dapat dinyatakan sebagai kandidat antikanker payudara.

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Section: Optimasi Geometri Senyawa Ujiunclassified

UJI AKTIVITAS ANTIKANKER PAYUDARA SENYAWA ANDROGRAFOLIDA DARI TUMBUHAN SAMBILOTO (Andrographis paniculata (Burm F) Ness.) TERHADAP HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER-2) SECARA IN SILICO

Suherlan

Rohayah

Fakih

2021

JIFF

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“…In recent years, it was shown that the embedding of the FeCo wires in a polymer matrix leads to magnetostrictive composite materials with enhanced inverse magnetostrictive effect. [ 15–19 ]…”

Section: S 33 M [× 10−12 M2 N−1] S 33 F [× 10−12 M2 N−1] mentioning

confidence: 99%

Twisting and Reverse Magnetic Field Effects on Energy Conversion of Magnetostrictive Wire Metal Matrix Composites

Yang

Wang

Seino

et al. 2020

Physica Rapid Research Ltrs

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Lightweight metal matrix composites have attracted a great attention for their technological application in aerospace, automotive, or sporting goods, and the multifunctionality of these composites will further expand the range of applications. Herein, a kind of lightweight 1–3 magnetostrictive FeCo/AlSi composites is investigated to evaluate the effects of the specific structure design and reverse magnetic field on the energy conversion under compression. The microstructure of the FeCo/AlSi composite before compression was observed, and the results indicate that there is a large bonding interface, which has the benefits of strain/stress transfer. Compared with the FeCo/AlSi composite with straight FeCo wire, a design with twisted FeCo wire significantly enhances the output performance of the magnetostrictive FeCo/AlSi composite. Furthermore, comparison of the output voltage for the FeCo/AlSi composite in the N–S mode (forward magnetization) and N–N mode (reverse magnetization) reveals that the reverse magnetization can improve the efficiency of the energy conversion notably. In addition, the results of the output voltage in the theoretical calculation are virtually consistent with that in practical measurement.

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“…[ 25 ] Meanwhile, magnetostrictive materials can convert magnetic energy into mechanical energy or the reverse, [ 26,27 ] and are used to build sensors and actuators. In the past decade, works on magnetostrictive alloys and composites, including clad plates, [ 28 ] short wire composites, [ 29 ] and long wire composites, [ 30 ] have been reported by our group. A new type of active magnetostrictive material has also been introduced as a biological sensor platform [ 31 ] in recent years.…”

Section: Introductionmentioning

confidence: 99%

A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

et al. 2020

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fever with or without chills, chest tightness, dry cough, and shortness of breath, while developing patchy to diffuse infiltration of the lungs, as shown radiographically in Figure 1. Identifying and monitoring SARS-CoV-2 infection has become crucially important. A recent projection of the transmission dynamics of SARS-CoV-2 [2] showed that longitudinal serological studies are desperately needed to determine the extent and duration of immunity to SARS-CoV-2. Even in the event of apparent elimination, maintenance of SARS-CoV-2 surveillance is still needed because of a possible resurgence of contagion. In the past, notable viruses have emerged suddenly from obscurity or anonymity, provoking concern from the point of view of immunology regarding their sustained epidemic transmission in naive human populations. More than 70% of these infections have been zoonotic, entering either directly from wild animal reservoirs or indirectly via an intermediate domestic animal host. [3] Ebola virus, avian influenza, human immunodeficiency virus (HIV), and SARS are all examples of zoonoses that have emerged from wild animals, presenting an increasingly serious threat to human health and economies worldwide. Figure 2 shows the trend in the number of people infected with SARS-CoV-2. [4] The spread of the severe acute respiratory syndrome coronavirus has changed the lives of people around the world with a huge impact on economies and societies. The development of wearable sensors that can continuously monitor the environment for viruses may become an important research area. Here, the state of the art of research on biosensor materials for virus detection is reviewed. A general description of the principles for virus detection is included, along with a critique of the experimental work dedicated to various virus sensors, and a summary of their detection limitations. The piezoelectric sensors used for the detection of human papilloma, vaccinia, dengue, Ebola, influenza A, human immunodeficiency, and hepatitis B viruses are examined in the first section; then the second part deals with magnetostrictive sensors for the detection of bacterial spores, proteins, and classical swine fever. In addition, progress related to early detection of COVID-19 (coronavirus disease 2019) is discussed in the final section, where remaining challenges in the field are also identified. It is believed that this review will guide material researchers in their future work of developing smart biosensors, which can further improve detection sensitivity in monitoring currently known and future virus threats.

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Fabrication, Modeling and Characterization of Magnetostrictive Short Fiber Composites

Cited by 24 publications

References 21 publications

UJI AKTIVITAS ANTIKANKER PAYUDARA SENYAWA ANDROGRAFOLIDA DARI TUMBUHAN SAMBILOTO (Andrographis paniculata (Burm F) Ness.) TERHADAP HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER-2) SECARA IN SILICO

UJI AKTIVITAS ANTIKANKER PAYUDARA SENYAWA ANDROGRAFOLIDA DARI TUMBUHAN SAMBILOTO (Andrographis paniculata (Burm F) Ness.) TERHADAP HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER-2) SECARA IN SILICO

Twisting and Reverse Magnetic Field Effects on Energy Conversion of Magnetostrictive Wire Metal Matrix Composites

A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

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