Fabrication and properties of zirconia/hydroxyapatite composite scaffold based on digital light processing

Cao, Ying; Shi, Tianshu; Jiao, Chen; Liang, Huixin; Chen, Ruoyu; Tian, Zongjun; Zou, Anchao; Yang, Youwen; Wei, Zhao; Wang, Changjiang; Shen, Lida

doi:10.1016/j.ceramint.2019.09.219

Cited by 105 publications

(53 citation statements)

References 45 publications

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“…e pore size and strut size of the sintered sca olds were about 650 μm and 450 μm, respectively, as shown in Figure 1. In general, porous bone sca olds was able to provide a favorable microenvironment for cell into-growth [28,29].…”

Section: Preparation Of Plla/cnts Composite Sca Oldmentioning

confidence: 99%

Crystallinity and Reinforcement in Poly-L-Lactic Acid Scaffold Induced by Carbon Nanotubes

Wang

Yang

et al. 2019

Advances in Polymer Technology

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Poly-L-Lactic Acid (PLLA) is a bioabsorbable implant material due to its favorable biocompatibility and inherent degradability, while the insufficient mechanical strength hinders its further bone repair application. In present work, carbon nanotubes (CNTs) were introduced into PLLA scaffolds fabricated via selective laser sintering. It was found that the crystallinity of PLLA increased considerably since CNTs could promote the orderly stacking of its molecular chains, thereby improving the mechanical strength of PLLA scaffold. Furthermore, the fracture surface analysis revealed that CNTs acted as a bridge across the cracks and hindered their further expansion. Moreover, CNTs pulled out from the matrix to consume a large amount of fracture energy, which enhanced the resistance to external forces. As a consequence, the compressive strength, Vickers hardness and tensile strength of the scaffold were enhanced by 22.7%, 58.8% and 17.6%, respectively. Besides, the cells exhibited good attachment, spreading and proliferation on the scaffold. This study demonstrated that PLLA/CNTs scaffold was a promising candidate as bone implant.

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Section: Preparation Of Plla/cnts Composite Sca Oldmentioning

confidence: 99%

Crystallinity and Reinforcement in Poly-L-Lactic Acid Scaffold Induced by Carbon Nanotubes

Wang

Yang

et al. 2019

Advances in Polymer Technology

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“…As one of the three elements of bone tissue engineering, artificial bone scaffold plays an extremely important role in bone repair process [1,2]. Ideally, scaffolds should have high porosities with open pore structure, over which cells can rapidly grow and develop into tissues that are viable [3,4].…”

Section: Introductionmentioning

confidence: 99%

Selective laser melted Fe-Mn bone scaffold: microstructure, corrosion behavior and cell response

Shuai

Yang

et al. 2020

Mater. Res. Express

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Iron metal possesses good biocompatibility and excellent mechanical strength, though it degrades too slowly. In this work, selective laser melting (SLM) was applied to fabricate iron-manganese (Fe-Mn) biodegradable scaffold. Results shown Fe-Mn scaffold exhibited a uniform pore structure with a porosity of 66.72±2.3%, which highly matched with as-designed model. Phase analysis revealed Fe-Mn scaffold mainly contained α-Fe, martensitic and austenitic phases. Due to the potential difference among these different phases, galvanic corrosion occurred in Fe matrix. In addition, a small amount of Mn distributed at grain boundaries also contributed to the formation of galvanic corrosion. Thus, the corrosion rate increased from 0.09±0.02 mm/year to 0.23±0.05 mm/year. The scaffold exhibited suitable mechanical properties with a yield strength of 137±8.4 MPa, an ultimate strength of 221.7±10.9 MPa. Moreover, cell assays demonstrated its good cytocompatibility. Taking these positive results into consideration, SLM processed Fe-Mn scaffold was a promising material for bone repair application.

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“…Girish et al [19,20] have studied the graphite particles reinforced Zn matrix composites and found that the hardness and strength were enhanced. However, they found it was difficult to form good interfacial bonding in metal matrix composite due to the large physical and chemical differences between the matrix and the reinforcing phase [21][22][23][24]. This will reduce the load transfer capacity of the enhancement phase [25][26][27][28].…”

Section: Introductionmentioning

confidence: 99%

In situ decomposition of Ti₂AlN promoted interfacial bonding in ZnAl-Ti₂AlN biocomposites for bone repair

Shuai

Xue

Gao

et al. 2020

Mater. Res. Express

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In this study, in situ decomposition of Ti 2 AlN was used to obtain strong interfacial bonding in Zn7Al-Ti 2 AlN composites prepared via laser melting. During the preparation process, the Al atoms in Ti 2 AlN could diffuse out of the lattice due to the weak bonding between Al and Ti, followed by easily diffusing into the liquid Zn7Al matrix. Consequently, the diffused Al could bond with the Al in Zn7Al matrix owing to their inherent chemical affinity, leading to a strong interfacial bonding in Zn7Al-Ti 2 AlN composites. This significantly improved the load transfer ability and prohibited the motion of dislocations in the composites. As a result, the hardness and compressive strength of Zn7Al-Ti 2 AlN composites were enhanced from 74 HV and 155 MPa to 80 HV and 205 MPa, respectively, which were more suitable for bone repair application. What's more, the composites also showed improved accelerated degradation and cytocompatibility.

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Fabrication and properties of zirconia/hydroxyapatite composite scaffold based on digital light processing

Abstract: Lida (2019) Fabrication and properties of zirconia/hydroxyapatite composite scaffold based on digital light processing. Ceramics International.

Cited by 105 publications

References 45 publications

Crystallinity and Reinforcement in Poly-L-Lactic Acid Scaffold Induced by Carbon Nanotubes

Crystallinity and Reinforcement in Poly-L-Lactic Acid Scaffold Induced by Carbon Nanotubes

Selective laser melted Fe-Mn bone scaffold: microstructure, corrosion behavior and cell response

In situ decomposition of Ti₂AlN promoted interfacial bonding in ZnAl-Ti₂AlN biocomposites for bone repair

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Fabrication and properties of zirconia/hydroxyapatite composite scaffold based on digital light processing

Abstract: Lida (2019) Fabrication and properties of zirconia/hydroxyapatite composite scaffold based on digital light processing. Ceramics International.

Cited by 105 publications

References 45 publications

Crystallinity and Reinforcement in Poly-L-Lactic Acid Scaffold Induced by Carbon Nanotubes

Crystallinity and Reinforcement in Poly-L-Lactic Acid Scaffold Induced by Carbon Nanotubes

Selective laser melted Fe-Mn bone scaffold: microstructure, corrosion behavior and cell response

In situ decomposition of Ti2AlN promoted interfacial bonding in ZnAl-Ti2AlN biocomposites for bone repair

Contact Info

Product

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About

In situ decomposition of Ti₂AlN promoted interfacial bonding in ZnAl-Ti₂AlN biocomposites for bone repair