Fabrication and preliminary evaluation of the osteogenic potential for micro-/nano-structured porous BCP ceramics

Optimal regenerative repair of large segmental bone defect in a goat model with osteoinductive calcium phosphate bioceramic implants

“…Previous studies from our group [ 11 , 14 , 15 ] and other groups [ 16 , 17 ] have shown that the special phase composition and porous structure of osteoinductive CaP ceramics enable it to interact with signal molecules and extracellular matrix in the host system, thus creating a local environment conducive to new bone formation. Additionally, a large number of studies [ [18] , [19] , [20] , [21] , [22] , [23] , [24] ] have proved that the process of cell, cell differentiation and osteogenesis during bone induction of calcium phosphate ceramics is consistent with the process of natural bone regeneration or reconstruction from the point of view of histology, material properties and material-body interaction, suggesting that artificial materials themselves can regulate the function of tissue regeneration and guide new bone formation through their own physical and chemical properties. Therefore, by optimizing the physiochemical properties of materials that are closely related to osteoconduction and osteoinduction, it is possible to achieve complete new bone regeneration of large bone defects.…”

Síntese de cerâmicas bifásicas de fosfato de cálcio pelo método Pechini

“…A literatura reporta que o uso de cerâmicas bifásicas de HAp/β-TCP tem um enorme impacto na capacidade de indução óssea in vivo devido à sua solubilidade diversificada no ambiente fisiológico e no microambiente iônico local, alcançando a formação ideal do crescimento do tecido ósseo, além disso resistência e tenacidade à fratura podem ser melhoradas com uma quantidade baixa da fase β-TCP [28,29].…”

Comparative studies on micromechanical properties and biological performances in hydroxyapatite ceramics with micro/nanocrystalline

“…In this study, the pop-in phenomenon was observed in the loaddisplacement curves of HA-CS and HA-TSS, but it was not found in HA-MAS (Figure 6A,B), which was partly due A survey of the published literature modeling of CMCs has been studied by a n ers. Processes that have been modeled CVD, 17,18 CVI, [19][20][21][22] and Sol-Gel Infiltrat of alumina matrix in eight-harness satin has been studied numerically in Ref. [ proaches used in the above work general ing the flow of a high viscosity resin thr and modeling the chemical reactions and during processing.…”

“…HA green body was then sintered by conventional sintering (CS), two-step sintering (TSS), and microwave-assisted sintering (MAS) method, A survey of the published literature shows that process modeling of CMCs has been studied by a number of researchers. Processes that have been modeled include RMI, 15,16 CVD, 17,18 CVI, [19][20][21][22] and Sol-Gel Infiltration. 23 Impregnation of alumina matrix in eight-harness satin Nextel 610 fabric has been studied numerically in Ref.…”

“…In the present study, the HA nanoceramics had the highest harness in the three kinds of ceramics, and the harness was increased with the F I G U R E 6 (A) The load-displacement curves, (B) the corresponding stiffness-displacement curves of the nanoindentation patterns of HA-CS, HA-TSS, and HA-MAS at the peak load of 10 mN, (C) The load-displacement curves and harness of indentations at the peak load ranged from 1 to 20 mN of HA-CS, HA-TSS, and HA-MAS A survey of the published literature shows that process modeling of CMCs has been studied by a number of researchers. Processes that have been modeled include RMI, 15,16 CVD, 17,18 CVI, [19][20][21][22] and Sol-Gel Infiltration. 23 Impregnation of alumina matrix in eight-harness satin Nextel 610 fabric has been studied numerically in Ref.…”