“…Protein-based nanoparticles have been commonly used as nanocarriers for curcumin because of their excellent biosafety, biocompatibility, and biodegradability [ 6 ]. Many proteins, for example, whey proteins, soy protein, and bovine serum albumin simply bind bioactives to the surface through hydrophobic interactions, resulting in a limited curcumin loading amount, and accelerated the instability of nanocomplexes [ 7 , 8 , 9 ]. Some proteins, for example, β-casein [ 10 ] and soy β-conglycinin [ 8 ], have a unique nanostructure that can be disassembled to expose more binding sites for curcumin, and then reassembled to encapsulate curcumin within the self-assembled structure, which enabled them to be developed as high-encapsulation-performance nanocarriers for curcumin by the self-assembly technology.…”