Self‐assembled pea vicilin nanoparticles as nanocarriers for improving the antioxidant activity, environmental stability and sustained‐release property of curcumin
Huihui Liu,
Zijun Wang,
Jingjing Xu
et al.
Abstract:BACKGROUNDThe application of curcumin (Cur) in the food industry is usually limited by its low water solubility and poor stability. This study aimed to fabricate self‐assembled nanoparticles using pea vicilin (7S) through a pH‐shifting method (pH 7–pH 12–pH 7) to develop water‐soluble nanocarriers of Cur.RESULTSIntrinsic fluorescence, far‐UV circular dichroism spectra and transmission electron microscopy analysis demonstrated that the structure of 7S could be unfolded at pH 12.0 and refolded when the pH shifte… Show more
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