Fabrication and Characterization of Gelatin Electrospun Fiber Containing Cardamom Essential Oil

Abstract

Background: Gelatin electrospun fibers incorporated with extracted cardamom Essential Oil (EO) were developed and characterized. Materials & Methods: The gelatin solutions were evaluated in terms of conductivity, morphology, fourier transform infrared spectroscopy, and the effect of cardamom EO on the gelatin fibers. Cardamom EO showed significant antioxidant activity with IC50 value of 5 μg/mL. The extract contained several active components including Cyclohexene, 1-methyl-4-(1-methylethylidene) and Eucalyptol (1.8-cineol) as the most abundant components. Results: The images of the scanning electron microscopy revealed formation of nanofibers from gelatin solution with significant entanglement. Furthermore, discrete beads were appeared by increasing the concentrations of cardamom EO in the gelatin fibers. Reduction in conductivity parameter of EO solutions could explain the observed defects. The fourier transform infrared spectra showed the formation of hydrogen bonds in gelatin fibers. The infrared as well as spectrophotometric spectra confirmed that EO was effectively involved in electrospun fibers. Conclusion: In conclusion, gelatin –a natural biopolymer, incorporated with cardamom EO forms smooth fabricated electrospun nanofibers.

Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties

“…The spectrum of GB showed the bands at 1653 cm −1 corresponding to the vibration of the amide carbonyl; at 1557 cm −1 it was associated with the stretching of the free amino groups [ 4 , 15 ], 1234 cm −1 was attributed to combination peaks between C−N stretching vibrations, N−H and the wagging vibrations from CH 2 groups stem from close amino acid residues [ 60 , 61 ]. These peaks are known as Amides I, II, and III.…”

“…The characteristic carbonyl absorption in 1596 cm −1 is replaced by the band in the 1550–1560 cm −1 region. This band corresponds to the auto-symmetrical vibrations of the COO-structure and is used as a diagnosis for the COO-group [ 16 , 61 ]. This ionization leads to the possible formation of anion-cation interaction.…”

Modification of chitosan with cellulose and gelatin for the removal of Cu2+, Fe2+, and Pb2+ from oily wastewater

“…NH stretching and hydrogen bonding appeared in the range of 3200–3923 cm −1 (amid A), CH stretching at 3080–3030 cm −1 , stretching vibrations of aliphatic groups at 2933 cm −1 , CO stretching at 1625 cm −1 (amid I), CN stretching and bending at 1508 cm −1 (amid II), and a combination of NH bending and CN stretching and symmetric deformation of NH 3 + at 1485–1440 cm −1 (amid III). [ 31 ] The usage of gelatin is dependent on its own chemical stability without deterioration, such as partial oxidation. FTIR analysis was performed to identify potential biomolecules, bonds responsible for the structural and functional stabilization of gelatin derived from fish scales.…”

Co‐encapsulation of lupulon and xanthohumol in lecithin‐based nanoliposomes developed by sonication method

“…Methanol was considered as blank and prepared in the same manner as the samples. The scavenging activity (%) was calculated using Equation (2) (Farahmand, Alavi, & Khalesi, ; Safari, Esteghlal, Keramat, & Khalesi, ):…”