Extrapyramidal side effects

Houltram, Brian; Scanlan, Mike

doi:10.7748/ns2004.07.18.43.39.c3641

Cited by 3 publications

(2 citation statements)

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“…Although drug therapy has been used to stabilize EPSs, a combination of drug therapy and nondrug therapy may be more effective in treating EPSs. Because drug therapy EPS may bring more new side effects (Burgyone et al, 2004;Houltram and Scanlan, 2004), but EHT is green and harmless and it can relieve some of the patients' symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…But drugs used to treat EPSs can produce new side effects. For example, when anticholinergic or antiparkinsonian medications are used as prophylactic therapy for EPSs, the potential risks of overdose include dry mouth, blurred vision, constipation, tachycardia, urinary hesitancy, dizziness, confusion, and the potential to aggravate tardive dyskinesia (Burgyone et al, 2004;Houltram and Scanlan, 2004).…”

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The Therapeutic Effect of Edible Horticultural Therapy on Extrapyramidal Symptoms in Patients with Schizophrenia

He¹,

Li²,

Zhou³

et al. 2021

horts

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Extrapyramidal symptoms (EPSs) are common adverse reactions to antipsychotics in patients with schizophrenia. The purpose of this study was to investigate the effects of edible horticultural therapy (EHT) on EPSs in schizophrenic patients. This study assessed the changes in psychopathological symptoms and extrapyramidal symptoms in patients with schizophrenia before and after participating in a six-session EHT. Forty schizophrenic patients, recruited from Wuhan Wudong Hospital, were randomly assigned to the EHT group (average age: 45.40 ± 13.960 years) or the control group (average age: 49.30 ± 12.516 years). The EHT program held weekly sessions from May 2020 to June 2020. A psychiatrist assessed the psychopathological symptoms and extrapyramidal symptoms of schizophrenic patients in both groups with the Chinese version of the Positive and Negative Syndromes Scale (PANSS) and the Rating Scale for Extrapyramidal Side Effects (RSESE). After six courses of horticultural therapy, the terms of positive, negative, and general symptoms on the PANSS significantly improved in the EHT group. Moreover, the EPSs were also significantly improved in the EHT group. However, there was no change in the PANSS and RSESE scores in the control group. This study shows that EHT has the potential to improve not only psychopathological symptoms but also EPSs in psychiatric patients. This adds new evidence for EHT as an adjunct to treatment for schizophrenia.

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confidence: 99%

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The Therapeutic Effect of Edible Horticultural Therapy on Extrapyramidal Symptoms in Patients with Schizophrenia

He¹,

Li²,

Zhou³

et al. 2021

horts

View full text Add to dashboard Cite

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Detection, Prevention, and Management of Extrapyramidal Symptoms

Courey¹

2007

The Journal for Nurse Practitioners

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Animal models of focal dystonia

Evinger

2005

Neurotherapeutics

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Summary: Animal models indicate that the abnormal movements of focal dystonia result from disordered sensorimotor integration. Sensorimotor integration involves a comparison of sensory information resulting from a movement with the sensory information expected from the movement. Unanticipated sensory signals identified by sensorimotor processing serve as signals to modify the ongoing movement or the planning for subsequent movements. Normally, this process is an effective mechanism to modify neural commands for ongoing movement or for movement planning. Animal models of the focal dystonias spasmodic torticollis, writer's cramp, and benign essential blepharospasm reveal different dysfunctions of sensorimotor integration through which dystonia can arise. Animal models of spasmodic torticollis demonstrate that modifications in a variety of regions are capable of creating abnormal head postures. These data indicate that disruption of neural signals in one structure may mutate the activity pattern of other elements of the neural circuits for movement. The animal model of writer's cramp demonstrates the importance of abnormal sensory processing in generating dystonic movements. Animal models of blepharospasm illustrate how disrupting motor adaptation can produce dystonia. Together, these models show mechanisms by which disruptions in sensorimotor integration can create dystonic movements.

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Extrapyramidal side effects

Cited by 3 publications

References 0 publications

The Therapeutic Effect of Edible Horticultural Therapy on Extrapyramidal Symptoms in Patients with Schizophrenia

The Therapeutic Effect of Edible Horticultural Therapy on Extrapyramidal Symptoms in Patients with Schizophrenia

Detection, Prevention, and Management of Extrapyramidal Symptoms

Animal models of focal dystonia

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