Extramedullary hematopoiesis with spinal cord compression in pachydermoperiostosis

Pachydermoperiostosis Associated with Myelofibrosis: A Rare Case Report

“…This association is rare according to 23 previous reports. [78] Vascular endothelial growth factor, hepatocyte growth factor, platelet-derived and the lack of regulation of PGE2 probably trigger the proliferation of fibroblasts and collagen deposition. [7] Treatment of this secondary MF has no consensus, with few reports of improvement of anemia and some of the fibrosis findings in bone marrow with corticotherapy (prednisolone, 0.5 mg/kg/day).…”