Extraction of phenolics and essential oil from dried sage (Salvia officinalis) using ethanol–water mixtures

Durling, Nicola E.; Catchpole, Owen J.; Grey, John B.; Webby, Rosemary F.; Mitchell, Kevin; Foo, Lai Yeap; Perry, Nigel B.

doi:10.1016/j.foodchem.2006.03.050

Cited by 302 publications

(204 citation statements)

References 27 publications

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“…This is in accordance with previous results reported for the hydroalcoholic extraction of several classes of polyphenols from various plant tissues, such as anthocyanins from blackcurrants (Nour et al 2013a), or phenolics from olive leaves (Japón-Luján et al 2006;Mylonaki et al 2008), dried sage (Salvia officinalis) (Durling et al 2007), mulberry leaves (Katsube et al 2006) and rice bran (Tabaraki & Nateghi 2011).…”

Section: Total Phenolics Contentsupporting

confidence: 93%

Optimization of ultrasound-assisted hydroalcoholic extraction of phenolic compounds from walnut leaves using response surface methodology

Nour

Trandafir

Cosmulescu

2016

Pharmaceutical Biology

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Context Walnut leaves are highly appreciated for their pharmacological effects and therapeutic properties which are mainly attributed to their high content of phenolic compounds. Objective This study optimizes ultrasound assisted hydroalcoholic extraction (UAE) of phenolic compounds from dried walnut leaves by the maximization of total phenolics content (TPC) and total flavanoids content (TFC) of the extracts. Materials and methods Optimal conditions with regard to ethanol concentration (X 1 : 12.17-95.83% v/v), extraction time (X 2 : 8.17-91.83 min) and liquid-to-solid ratio (X 3 : 4.96-25.04 v/w) were identified using central composite design combined with response surface methodology. A high-performance liquid chromatography method with diode-array detection was used to quantify phenolic acids (gallic, vanillic, chlorogenic, caffeic, syringic, p-coumaric, ferulic, sinapic, salicylic, ellagic and trans-cinnamic), flavonoids (catechin, epicatechin, rutin, myricetin and quercetin) and juglone in the extracts. Results Liquid-to-solid ratio and ethanol concentration proved to be the primary factors affecting the extraction efficiency. The maximum predicted TPC, under the optimized conditions (61% ethanol concentration, 51.28 min extraction time and 4.96 v/w liquid-to-solid ratio) was 10125.4 mg gallic acid equivalents per liter while maximum TFC (2925 mg quercetin equivalents per liter) occurred at 67.83% ethanol concentration, 4.96 v/w liquid-to-solid ratio and 49.37 min extraction time. High significant correlations were found between antioxidant activity and both TPC (R 2 ¼ 0.81) and TFC (R 2 ¼ 0.78). Discussion and conclusion Extracts very rich in polyphenols could be obtained from walnut leaves by using UAE, aimed at preparing dietary supplements, nutraceuticals or functional food ingredients. ARTICLE HISTORY

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Section: Total Phenolics Contentsupporting

confidence: 93%

Optimization of ultrasound-assisted hydroalcoholic extraction of phenolic compounds from walnut leaves using response surface methodology

Nour

Trandafir

Cosmulescu

2016

Pharmaceutical Biology

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“…Due to their chemical structure, CA and RA are conventionally extracted by methanol and acetone [15,24,25]. Other solvents have been used such as ethanol and water or a mixture of both [24].…”

Section: Introductionmentioning

confidence: 99%

“…Other solvents have been used such as ethanol and water or a mixture of both [24]. Considering sustainable and safe extraction, there is a major interest in the use of a mixture of ethanol and water as an extraction solvent, each of these solvents being classified as GRAS solvents.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound versus microwave as green processes for extraction of rosmarinic, carnosic and ursolic acids from rosemary

Jacotet-Navarro

Rombaut

Fabiano‐Tixier

et al. 2015

Ultrasonics Sonochemistry

112

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“…The extraction of flavonoids can be improved as a result of enhancement of component solubility in the extraction solvent, diffusion rate, solvent viscosity, and the decreased surface tension (Ju & Howard 2003). However, we cannot say that this trend will continue even for high MP, because a further increment of MP may result in an increase in the temperature of the extraction solvent, the resulting excessive heat can influence the stability of flavonoids and phenolic components due to destabilisation by a reaction with other chemical components or enzymes, chemical, and enzymatic degradation or thermal decomposition, thus reducing the extraction efficiency (Durling et al 2007). Figure 2A reveals the effect of interaction between MP and SSR on TP.…”

mentioning

confidence: 99%

Optimisation of microwave-assisted extraction of flavonoids and phenolics from celery (Apium graveolens L.) leaves by response surface methodology

He¹,

Li²,

Zhang³

et al. 2016

Czech J. Food Sci.

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The conditions for microwave-assisted extraction (MAE) of total flavonoids (TF) and total phenols (TP), and antioxidant activity from celery (Apium graveolens L.) leaves by response surface methodology (RSM) were optimised. The 3-level, 3-factorial Box-Behnken design (BBD) was employed to study three main extraction conditions: microwave power (300–500 W), solid-solvent ratio (15–30 ml/g), and ethanol concentration (50–80%). It was found that microwave power of 500 W at 30 ml/g solid-solvent ratio with 75.6% (v/v) ethanol concentration was the most optimum conditions for the extraction of TF and TP from celery leaves with the consequent high antioxidant activity measured by the DPPH inhibition rate. Using the optimum extraction conditions, the extraction yields of TF and TP were 0.62 g RUE/100 g DW, 3.01 g GAE/100 g DW, respectively, and the DPPH inhibition rate was 88%. The results indicated that the nutritional quality of celery (Apium graveolens L.) leaves could be improved significantly by optimising the extraction process of MAE using response surface methodology.

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Extraction of phenolics and essential oil from dried sage (Salvia officinalis) using ethanol–water mixtures

Cited by 302 publications

References 27 publications

Optimization of ultrasound-assisted hydroalcoholic extraction of phenolic compounds from walnut leaves using response surface methodology

Optimization of ultrasound-assisted hydroalcoholic extraction of phenolic compounds from walnut leaves using response surface methodology

Ultrasound versus microwave as green processes for extraction of rosmarinic, carnosic and ursolic acids from rosemary

Optimisation of microwave-assisted extraction of flavonoids and phenolics from celery (Apium graveolens L.) leaves by response surface methodology

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