Extraction of Bioactive Compounds from Medicinal Plants and Herbs

Stéphane, Fongang Fotsing Yannick; Jules, Bankeu Kezetas Jean; Batiha, Gaber El‐Saber; Ali, Iftikhar; Bruno, Lenta Ndjakou

doi:10.5772/intechopen.98602

Cited by 45 publications

(27 citation statements)

References 87 publications

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“…However, these techniques require a highly equipped and expensive experimental setup. 63 − 66 A brief summary of the various methods of extraction is reported in Table 2 .…”

Section: Introductionmentioning

confidence: 99%

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Green Route Synthesis and Characterization Techniques of Silver Nanoparticles and Their Biological Adeptness

et al. 2022

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The development of the most reliable and green techniques for nanoparticle synthesis is an emerging step in the area of green nanotechnology. Many conventional approaches used for nanoparticle (NP) synthesis are expensive, deadly, and nonenvironmental. In this new era of nanotechnology, to overcome such concerns, natural sources which work as capping and reducing agents, including bacteria, fungi, biopolymers, and plants, are suitable candidates for synthesizing AgNPs. The surface morphology and applications of AgNPs are significantly pretentious to the experimental conditions by which they are synthesized. Available scattered information on the synthesis of AgNPs comprises the influence of altered constraints and characterization methods such as FTIR, UV–vis, DLS, SEM, TEM, XRD, EDX, etc. and their properties and applications. This review focuses on all the above-mentioned natural sources that have been used for AgNP synthesis recently. The green routes to synthesize AgNPs have established effective applications in various areas, including biosensors, magnetic resonance imaging (MRI), cancer treatment, surface-enhanced Raman spectroscopy (SERS), antimicrobial agents, drug delivery, gene therapy, DNA analysis, etc. The existing boundaries and prospects for metal nanoparticle synthesis by the green route are also discussed herein.

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“…However, these techniques require a highly equipped and expensive experimental setup. 63 − 66 A brief summary of the various methods of extraction is reported in Table 2 .…”

Section: Introductionmentioning

confidence: 99%

“…These techniques require less extraction solvent and less extraction time with efficient extraction yield. However, these techniques require a highly equipped and expensive experimental setup. − A brief summary of the various methods of extraction is reported in Table .…”

Section: Introductionmentioning

confidence: 99%

Green Route Synthesis and Characterization Techniques of Silver Nanoparticles and Their Biological Adeptness

et al. 2022

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“…The bioactive compounds found in medicinal plants give them a broad spectrum of pharmacological and therapeutic activities. Phenolics, organosulfur compounds, flavonoids, coumarins, terpenoids, alkaloids, and steroids are some of the bioactive substances found in medicinal plants that accord their pharmacotherapeutic benefits [ 240 ]. For instance, bioactive peptides found in plants have been reported to have little or no toxicity, do not accumulate in the body, and are very effective even at low concentrations.…”

Section: Discussionmentioning

confidence: 99%

Immune System and Epidemics: The Role of African Indigenous Bioactive Substances

et al. 2023

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With over 6 million coronavirus pandemic deaths, the African continent reported the lowest death rate despite having a high disease burden. The African community’s resilience to the pandemic has been attributed to climate and weather conditions, herd immunity, repeated exposure to infectious organisms that help stimulate the immune system, and a disproportionately large youth population. In addition, functional foods, herbal remedies, and dietary supplements contain micronutrients and bioactive compounds that can help boost the immune system. This review identified significant traditional fermented foods and herbal remedies available within the African continent with the potential to boost the immune system in epidemics and pandemics. Methodology: Databases, such as PubMed, the Web of Science, and Scopus, were searched using relevant search terms to identify traditional African fermented foods and medicinal plants with immune-boosting or antiviral capabilities. Cereal-based fermented foods, meat-, and fish-based fermented foods, and dairy-based fermented foods containing antioxidants, immunomodulatory effects, probiotics, vitamins, and peptides were identified and discussed. In addition, nine herbal remedies and spices belonging to eight plant families have antioxidant, immunomodulatory, anti-inflammatory, neuroprotective, hepatoprotective, cardioprotective, and antiviral properties. Peptides, flavonoids, alkaloids, sterols, ascorbic acid, minerals, vitamins, and saponins are some of the bioactive compounds in the remedies. Bioactive compounds in food and plants significantly support the immune system and help increase resistance against infectious diseases. The variety of food and medicinal plants found on the African continent could play an essential role in providing community resilience against infectious diseases during epidemics and pandemics. The African continent should investigate nutritional, herbal, and environmental factors that support healthy living and longevity.

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“…The samples used in powder form have smaller homogenized particles and this aspect leads to better contact on the surface with the extraction solvents. This special pre-preparation is important because, in order for an efficient extraction to take place, the solvent must come into contact with the target analytes and having a particle size as small as possible is ideal for efficient extraction [28][29][30].…”

Section: Sample Preparationmentioning

confidence: 99%

Comparative Study of Natural Antioxidants from Glycine max, Anethum graveolensand Pimpinella anisum Seed and Sprout Extracts Obtained by Ultrasound-Assisted Extraction

et al. 2022

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The study aimed to evaluate the antioxidant potential of sprout and seed extracts from three species of plants, namely Glycine max (GMsp-sprouts, GMsd-seeds), Anethum graveolens (AGsp-sprouts, AGsd-seeds) and Pimpinella anisum (PAsp-sprouts, PAsd-seeds), which are widely accepted by consumers and have various applications in food flavoring, and also in natural medical treatments in the pharmaceutical industries. These plants are rich in valuable compounds that show a remarkable antioxidant power and are associated with many health benefits. Ethanol extracts were obtained by ultrasound-assisted extraction and they were comparatively evaluated for their in vitro antioxidant properties. The extracts were characterized by HPTLC, HPLC-DAD, total phenol content (TPC), total flavonoid content (TFC) analysis and antioxidant activities with different assays, such as total antioxidant capacity (TAC), 2,2′-azino-bis (3- ethylbenzothiazoline-6-sulfonic acid) radical cation decolorization assay (ABTS), 1,1-diphenyl 1-2-picryl-hydrazyl (DPPH) and iron binding ability of chelators. Our results showed that the sprout and seed extracts of the studied plants exhibited a high content of phytochemicals and promising antioxidant properties. The highest polyphenols content was detected for AGsd (53.02 ± 0.57 mg/g DW), PAsd (48.75 ± 0.34 mg/g DW) and the highest flavonoids content for PAsp (26.84 ± 0.57 mg/g DW). Moreover, the presence of valuable compounds was demonstrated by using HPTLC, FT-IR and HPLC-DAD techniques. In order to have a better understanding of the relationship between the biological properties and the electronic structure, a molecular modelling study of genistein was also conducted. Our approach to the comparative assessment of these three plant species was based on a priori knowledge from literature data; however, this study demonstrated that these plant extracts of seeds and also sprouts are excellent sources of natural antioxidants. Significant additional differences that were found in the phytochemical composition could be exploited in future research for pharmaceutical purposes.

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Extraction of Bioactive Compounds from Medicinal Plants and Herbs

Cited by 45 publications

References 87 publications

Green Route Synthesis and Characterization Techniques of Silver Nanoparticles and Their Biological Adeptness

Green Route Synthesis and Characterization Techniques of Silver Nanoparticles and Their Biological Adeptness

Immune System and Epidemics: The Role of African Indigenous Bioactive Substances

Comparative Study of Natural Antioxidants from Glycine max, Anethum graveolensand Pimpinella anisum Seed and Sprout Extracts Obtained by Ultrasound-Assisted Extraction

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