Extraction of anthocyanins and luteolin from Arrabidaea chica by sequential extraction in fixed bed using supercritical CO2, ethanol and water as solvents

Ethnobotanical study of medicinal plants by population of Valley of Juruena Region, Legal Amazon, Mato Grosso, Brazil

“…A flavone, 7,4'-dihydroxy-5-methoxyflavone was later isolated by Takemura et al (1995). The principal components of anthocyanins found in Arrabidaea chica were later confirmed by subsequent studies (Paula et al, 2013(Paula et al, , 2014 and that they are of type 3-desoxyanthocyanidins, namely 6,7,3ʹ-trihydroxy-5-dimetoxifl-avilium and 6,7,3ʹ,4ʹ-tetrahydroxi-5-methoxy-flavylium, known as; and 6-dihydroxy-5,4ʹ-dimetoxyflavilium, known as carajurone and carajurin respectively.…”

“…The activities include among others, hepatoprotective (hydroethanolic extract), antimicrobial (hydroethanolic and dichloromethane extracts), wound healing (methanolic and ethanolic extracts), anti-inflammatory (aqueous extract), analgesic, antihelminthic and anti-Leshmania activities (hexanic extract) (Barbosa et al, 2008;Höfling et al, 2010;Mafioleti et al, 2013;Paula et al, 2014;Rodrigues et al, 2014). Recently also the ethanol and aqueous extracts of Arrabidaea chica were shown to be anti-inflammatory, antiangiogenic and antiproliferative activities in a murine model (Michel et al, 2015).…”

OBTENÇÃO DE EXTRATOS DE Melia azedarach L. POR PROCESSO SEQUENCIAL EM LEITO FIXO USANDO scCO2, ETANOL E ÁGUA COMO SOLVENTES

“…A extração foi realizada em quatro etapas sequencias a 300 bar e 50 °C, como apresentado na Figura 1, em uma unidade de extração descrita em diversos trabalhos (Paula et al, 2013;Paula et al, 2014;Garmus et al, 2014). Além disso, uma armadilha "Porapak" foi conectada juntamente ao sistema de coleta de CO 2 .…”

“…O dióxido de carbono é o solvente mais utilizado no estado de fluido supercrítico pois, quando aplicado a alimentos e fármacos, não gera resíduos tóxicos. Além disso, técnicas de extração que envolvem diversas etapas sequenciais com scCO 2 e combinações entre scCO 2 , etanol e água têm obtido grande sucesso para extração e fracionamento de compostos fenólicos (Seabra et al, 2010;Paula et al, 2013;Paula et al, 2014;Garmus et al, 2014). A água e o etanol possuem polaridades diferentes à do scCO 2 e não há restrições de órgãos governamentais e ambientais quanto ao seu uso.…”

Recent patents on the application of bioactive compounds in food: a short review

“…Important factors in the process are solvent type, extraction time and temperature [9]. Solvents or co solvents with different polarities such as ethanol and water [5,10,11] and/or organic solvents [4,6,7] can be employed for solid-liquid extractions in heat-reflux systems. Furthermore, non-conventional methods (ultrasound, pulsed electric field, enzyme digestion, extrusion, microwave heating, ohmic heating, supercritical fluids) are more environment friendly due to decreased use of synthetic and organic chemicals and reduced operational time, enhancing extract yield and quality [9].…”