Extraction methods and chemical standardization of botanicals and herbal preparations

Ong, Eng Shi

doi:10.1016/j.jchromb.2004.07.041

Cited by 89 publications

(10 citation statements)

References 73 publications

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“…Various drying techniques, hot-air, microwave, and freeze drying, and operating conditions have been applied in the preparation of botanical samples [25, 26]. Herbal extracts might vary depending on different operating conditions including temperature, relative humidity, and air velocity even in the same drying process [27]. Drying has significant effects on the production of quality medicinal plants.…”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Sulfur Compounds Contents and Antiobesity Properties of Allium hookeri Prepared by Different Drying Methods

Yang

Kim

Heo

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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Despite the nutritional and medicinal values of Allium hookeri, its unique flavor (onion or garlic taste and smell) coming from sulfur containing compounds limits its usage as functional food. For comparative study, A. hookeri roots were prepared under two different drying conditions, namely, low-temperature drying that minimizes the volatilization of sulfur components and hot-air drying that minimizes the garlic odor and spicy taste of A. hookeri. In GC/MS olfactory system, the odorous chemicals and organosulfur compounds such as diallyl trisulfide, dimethyl trisulfide, and dipropyl trisulfide were significantly decreased in hot-air drying compared to low-temperature drying. The spiciness and saltiness taste were noticeably reduced, while sourness, sweetness, and umami taste were significantly increased in hot-air dried A. hookeri according to electronic tongue. Although the content of volatile sulfur components was present at lower level, the administration of hot-air dried A. hookeri extract (100 mg/kg p.o.) apparently prevented the body weight gain and improved insulin resistance in C57BL/6J obese mice receiving high fat diet. Results suggested that the hot-air dried A. hookeri possessing better taste and odor might be available as functional crop and bioactive diet supplement for the prevention and/or treatment of obesity.

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Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Sulfur Compounds Contents and Antiobesity Properties of Allium hookeri Prepared by Different Drying Methods

Yang

Kim

Heo

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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“…Considering that one of the criteria for selecting a chemical marker in a plant extract is the fact that this compound is responsible for the pharmacological effect elicited by the extract ( Ding et al, 2017 , Kunle, 2012 , Ong, 2004 ), we chose (-)-epicatechin and rutin as potential chemical markers of C. mexicana leaves extracts. In order to identify these phenolic compounds in specimens of C. mexicana from different collections, methanolic and ethanolic leaf extracts obtained from two different years (2018 and 2016) were analyzed in addition to the extracts prepared from C. mexicana leaves (batch 2019).…”

Section: Resultsmentioning

confidence: 99%

Development of a quantified herbal extract of hawthorn Crataegus mexicana leaves with vasodilator effect

Ornelas-Lim

Luna-Vázquez

Rojas‐Molina

et al. 2021

Saudi Pharmaceutical Journal

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Hawthorn ( Crataegus spp .) has been used for the treatment of several heart diseases and hypertension. The studies carried out on several hawthorn species have led to the development of standardized extracts useful in the cure of mild chronic cardiac diseases. In Mexico, the most common Crataegus species are C. mexicana and C. gracilior . Decoctions prepared from the fruits and leaves of these species have been employed to the treat respiratory diseases, tachycardia and to improve coronary blood flow. Considering that to date there are no reports of the use of Mexican Crataegus species to treat cardiovascular diseases, we propose an analytical method to obtain a quantified extract of Crataegus mexicana leaves for the development of a standardized extract with therapeutic value in cardiovascular diseases as an alternative source to the extracts obtained from Crataegus species of European and Asian origin. Therefore, the aim of this study was to obtain an extract prepared from C. mexicana leaves with the highest vasodilator activity to select the optimal chemical marker to stablish and validate a reversed-phase high-performance liquid chromatography (RPHPLC-DAD) analytical method for obtaining a quantified extract with vasodilator effect. The results obtained from the analytical method validation, which was carried out according to the guidelines stablished in the Eurachem Guide and the ICH guidelines proved that the RPHPLC-DAD method we developed was specific, precise, accurate, and showed good linearity over the concentration range of 3 – 21 µg/ml for (-)-epicatechin and rutin, which were selected as chemical markers.

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“…The titles of review articles published in this stage do not contain AA; nevertheless, the content is, to some extent, related to AA. Some review articles published in 2004 focused on the toxicity of herbal medicines owing to their wide use and ease of availability, and gradually revealed their safety [73, 74]; moreover, the quality control of herbal medicines became a higher priority [75, 76]. In 2005, CHN and AA nephropathy were extensively discussed by Colson and De Broe, who explored kidney injury from complementary or alternative medicines [77].…”

Section: Resultsmentioning

confidence: 99%

Worldwide research trends on aristolochic acids (1957–2017): Suggestions for researchers

et al. 2019

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Aristolochic acids and their derivatives are components of many traditional medicines that have been used for thousands of years, particularly in Asian countries. To study the trends of research into aristolochic acids and provide suggestions for future study, we performed the following work. In this paper, we performed a bibliometric analysis using CiteSpace and HistCite software. We reviewed the three phases of the development of aristolochic acids by using bibliometrics. In addition, we performed a longitudinal review of published review articles over 60 years: 1,217 articles and 189 review articles on the history of aristolochic acid research published between 1957 and 2017 were analyzed. The performances of relevant countries, institutions, and authors are presented; the evolutionary trends of different categories are revealed; the history of research into aristolochic acids is divided into three phases, each of which has unique characteristics; and a roadmap of the historical overview of aristolochic acid research is finally established. Finally, five pertinent suggestions for future research into aristolochic acid are offered: (1) The study of the antitumor efficacy of aristolochic acids is of value; (2) The immune activity of aristolochic acids should be explored further; (3) Researchers should perform a thorough overview of the discovery of naturally occurring aristolochic acids; (4) More efforts should be directed toward exploring the correlation between aristolochic acid mutational signature and various cancers; (5) Further efforts should be devoted to the research and review work related to analytical chemistry. Our study is expected to benefit researchers in shaping future research directions.

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Extraction methods and chemical standardization of botanicals and herbal preparations

Cited by 89 publications

References 73 publications

Comparative Evaluation of Sulfur Compounds Contents and Antiobesity Properties of Allium hookeri Prepared by Different Drying Methods

Comparative Evaluation of Sulfur Compounds Contents and Antiobesity Properties of Allium hookeri Prepared by Different Drying Methods

Development of a quantified herbal extract of hawthorn Crataegus mexicana leaves with vasodilator effect

Worldwide research trends on aristolochic acids (1957–2017): Suggestions for researchers

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