Extraction conditions for Rosa gallica petal extracts with anti-skin aging activities

Abstract

The anti-skin inflammatory activities of rose petal extracts have been described in our previous study. Because skin inflammation is closely linked to skin aging, our study investigated the effects of Rosa gallica petals on skin aging-related activities such as skin whitening and anti-wrinkle properties. Each sample was prepared via extraction using different ethanol ratios with the objective of evaluationg optimal extraction conditions for industrial application. Aqueous 50% (v/v) EtOH extract of R. gallica petal significantly suppressed tyrosinase activity, melanin production, and solar UV-induced matrix metalloproteinase-1, a hall mark of wrinkle formation. In addition, the aqueous 50% (v/v) EtOH extract showed the highest antioxidative effect and had highest flavonoid contents, consistent with the reported anti-aging effects. Overall, our findings suggest that R. gallica petals extracts exhibit antiaging effects. Furthermore, 50% EtOH extraction, in particular, was optimal for the highest anti-aging, and antioxidative effects as well as to obtain the highest flavonoid content.

Oral Administration of Rosa gallica Prevents UVB−Induced Skin Aging through Targeting the c−Raf Signaling Axis

“…In the current study, RPE was orally administered to mice and its protective effect against skin aging was examined. While a previous study reported the effect of RPE against UVB−induced skin aging under in vitro conditions [ 24 , 37 ], the efficacy of RPE in vivo was unknown. This is the first report to demonstrate that oral administration of Rosa gallica can block UVB−mediated skin aging in vivo without any noticeable toxicity.…”

“…In particular, Rosa gallica is one of the most commonly used Rosa species for cosmetic, medicinal, and culinary purposes [ 22 , 23 ]. Although the potential of the Rosa gallica extract to prevent biomarkers of skin aging in vitro has been reported [ 24 ], there has been no study demonstrating the anti−skin aging effect of Rosa gallica in vivo. Moreover, active ingredients responsible for the bioactivity of Rosa gallica and Rosa species are poorly understood.…”

Phytochemical and pharmacological study of Rosa x gallica L. georgian cultivar essential oil production waste

“…Anthocyanins are claimed to suppress natural oxidative process, to protect the body from neurodegenerative and cardiovascular diseases [7] and have antidiabetic effects [8]. Cosmetology studies have confirmed R. x gallica's effects on skin rehydration, minimizing the production of age-related wrinkles, nourishing the epidermis, improving skin elasticity, and having a rejuvenating impact [9].…”

Rosa platyacantha Schrenk from Kazakhstan—Natural Source of Bioactive Compounds with Cosmetic Significance

“…R. canina hip powder, containing seeds and shells, was recently shown to increase cell longevity, improve skin wrinkles, moisture, and elasticity [ 4 ]. Petal extract of R. gallica decreased the expression of solar UV-induced MMP-1, which is a hallmark of wrinkle formation [ 18 ]. Extracts and compounds isolated from R. canina, R. gallica , and R. rugosa have been extensively studied to assess their efficacy as potential skin-lightening ingredients [ 19 , 20 , 21 ].…”