Extract of haruan (Channa striata) extract increasing reepithelialisation count in wound healing process on wistar rat’s buccal mucosa

Abstract

The purpose of this study was to evaluate the microorganisms found on used toothbrushes. In this study 25 toothbrushes were investigated, 10 toothbrushes were used less than 3 months, 10 toothbrushes have been used for 3-6 months, and 5 toothbrushes have been used for more than 6 months. Some gram-positive coccus, such as Staphylococcus, Streptococcus and Diplococcus. The results showed there were microbial harbored of used toothbrushes. Toothbrushes that have been used for 6 months were harbored more microorganisms than the toothbrushes that have been used less than 3 months and 3-6 months. It can be concluded that the longer using time of toothbrush the more increase of microorganism amount found on toothbrush. Key words: toothbrush, microorganism contaminationCorrespondence: Asmawati, Department of Oral Biology, Faculty of Dentistry, Hasanuddin University, Jl. Perintis Kemerdekaan Km.10, Makassar, Indonesia. E-mail: asmaamin68@yahoo.com INTRODUCTIONOral health of Indonesian people is still a major concern. The objective of oral health is to gain a healthy mouth and good dentition, and also a good function of speech and mastication.1 Oral health status is influenced by four important factors; namely heredity, environment (physical and social culture), behavior, and health service. Of those four factors, behavior plays an important role in oral health status and could influence environment and health service factors.

EFEKTIVITAS PEMBERIAN EKSTRAK IKAN HARUAN (Channa striata) TERHADAP JUMLAH NEUTROFIL PADA PROSES PENYEMBUHAN ULKUS TRAUMATIKUS

“…Inflamasi merupakan fase pertama dari proses penyambuhan luka. 8 Fase ini berlangsung pada 24 jam pertama sampai hari ke-3, dengan adanya pergerakan neutrofil ke pembuluh darah ke luka meningkat pada 24-48 jam dan penurunan setelah hari ke-3. Fase ditandai dengan peningkatan aliran darah dan permeabilitas kapiler darah diikuti dengan vasodilatasi pembuluh darah.…”

“…7 Berdasarkan penelitian yang dilakukan Setiawan (2015) 16 Berdasarkan statistik deskriptif pada rerata hasil penelitian, didapatkan bahwa kelompok hari ke-1 hari memiliki jumlah neutrofil lebih tinggi daripada kelompok hari ke-3 pada seluruh kelompok kontrol dan perlakuan.Pada proses penyembuhan ulkus traumatikus inflamasi merupakan fase pertama dari proses penyambuhan luka. 8 Neutrofil merupakan sel pertama yang dilepaskan saat terjadi luka. Fase ini berlangsung pada 24 jam pertama sampai hari ke-3, dengan adanya pergerakan neutrofil ke pembuluh darah menuju luka meningkat pada 24-48 jam dan penurunan setelah hari ke-3, sehingga jumlah neutrofil hari ke-1 lebih banyak dibandingkan dengan hari ke-3.…”

Efficacy of mengkudu leaves extract (morinda citrifolia) on wound healing rate post tooth extraction in white rats (rattus norvegicus)

“…Wound healing can be inhibited if the wound is not treated properly thus it can lead to complications. [4][5][6][7][8][9] Our ancestors have used herbal plants as medicine for centuries. The ancestors saw that plants used as food can also alleviate or cure disease.…”

“…Mengkudu is known as noni in Hawaii, mulberry or nuna in India, and nhaut in South Asia. [8][9][10][11][12] Mengkudu leaves compressed on wounds have been shown to lead to wound healing. The active ingredients found in mengkudu leaves are saponins, triterpens, tannins, alkaloids, iridoid glycosides, and flavonoids.…”

“…8 Mengkudu leaves extract improve the wound healing process and reduce healing time by binding to platelet-derived growth factor (PDGF) and adenosine (A2A) receptors that accelerate wound healing. [7][8][9][10][11][12] The purpose of this study was to determine the efficacy of mengkudu leaves (morindacitrifolia) on wound healing post tooth extraction in white rats (rattusnorvegicus).…”