Extracorporeal Circulation With Low Systemic Heparinization During Lung Transplantation

When Therapy Is Confounded With Approach: Retrospective Studies of Transfusion-Related Outcomes After Lung Transplantation

“…Varying degrees of bleeding may be encountered depending on the mechanical circulatory support selected (venovenous, venoarterial, or venoarterial venous ECMO, or cardiopulmonary bypass) and the anticoagulation strategy required. 13 Because mechanical circulatory support either can be used electively or as a rescue for severe primary graft dysfunction or cardiopulmonary compromise, variability in surgical strategy makes understanding the relationships of bleeding, transfusion, primary graft dysfunction, and mortality a challenge. However, because several studies have demonstrated an outcome benefit by using an elective venoarterial ECMO strategy, this source of variability may be reduced going forward.…”