Extracorporal Shock Wave Therapy in the Treatment of Peyronie&amp;rsquo;s Disease

Hauck, Ekkehard W.; Altinkilic, B.; Ludwig, Maria Cristina Flurin; Lüdecke, Gerson; Schroeder‐Printzen, I.; Arens, Christoph; Weidner, W.

doi:10.1159/000020359

Cited by 63 publications

(32 citation statements)

References 20 publications

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“…[52][53][54][55] The rationale for this approach is not yet known, but has been suggested to have several possible mechanisms including (1) direct damage to the plaque resulting in an inflammatory reaction with increased macrophage activity yielding plaque lysis, (2) as a result of changes in plaque configuration and inflammatory response following ESWT, there may be improved vascularity with plaque resorption, and (3) repeated trauma to the area of plaque and deformity results in a contralateral scarring, which may shorten the contralateral side and result in a false straightening of the penis. There have been limited studies on ESWT to soft tissue.…”

Section: External Energy Therapymentioning

confidence: 99%

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Review of current nonsurgical management of Peyronie's disease

Levine

2003

Int J Impot Res

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The current nonsurgical treatment options for men with Peyronie's disease is reviewed. The treatments currently employed and published in the English literature are discussed. A wide variety of nonsurgical treatment options are available to the practicing physician, including oral and topical medications, intralesional injection therapy, as well as employing external energy sources to drive medicine into the tunica albuginea by iontophoresis or direct stimulation of plaque change by shock wave therapy. Nonsurgical treatment of Peyronie's disease clearly has a place in the armamentarium of the practicing urologist. Oral therapy appears to have little therapeutic benefit. Injection and topical approaches deserve further attention. Yet, no single treatment stands out as the most effective remedy for all men with Peyronie's disease. Further controlled, large-scale studies are necessary to establish the benefits of these nonsurgical approaches. In the meantime, combination therapy appears to make sense in the nonsurgical treatment of men with Peyronie's disease.

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Section: External Energy Therapymentioning

confidence: 99%

“…Pain improved in 77-100%, overall general improvement was reported in 0-72%, and coitus was reported enhanced in 20-62% of patients. The study by Hauck et al 55 attempted to approximate a placebo-controlled trial. In this study, 20 men underwent ESWT vs 23 who received an oral placebo for 6 months.…”

Section: External Energy Therapymentioning

confidence: 99%

Review of current nonsurgical management of Peyronie's disease

Levine

2003

Int J Impot Res

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“…9,10 Meanwhile, further published articles have reported subjective good results after shockwave treatment. 11,12 All of the above-mentioned studies recruited inhomogeneous patient groups and evaluated only the subjective (symptom) change. We attempted to assess the objective long-term changes in patients with Peyronie's disease after treatment with extracorporeal shockwaves.…”

Section: Introduction P Eyronie's Disease Is Characterized By a Lesiomentioning

confidence: 99%

Objective and Subjective Changes in Patients with Peyronie's Disease after Management with Shockwave Therapy

Michel

Ptaschnyk

Musial

et al. 2003

Journal of Endourology

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“…Various hypotheses about its mechanism of action exist, including direct damage to the plaque, resulting in an inflammatory reaction with increased macrophage activity leading to plaque lysis, improved vascularity resulting in plaque resorption, and the creation of contralateral scarring of the penis resulting in 'false' straightening. 73 Hauck et al 74 randomized 43 men to ESWT or oral placebo for 6 months. No significant effect was noted in terms of curvature, plaque size or subjective improvement in sexual function or rigidity.…”

Section: Penile Electroshock Wave Therapy (Eswt)mentioning

confidence: 99%