“…Unlike the CNS injury, the distal portion of axons and myelin detritus are lysed and eliminated due to the activation of Schwann cells and the recruitment of macrophages, paving the way for removing inhibitory factors [ 16 ]. Notably, Collagen I, III, IV, V, VI and laminin exhibit significantly elevated deposition in Schwann and perineurial cells during peripheral injuries and neuropathies [ 17 ].…”