Collagen for neural tissue engineering: Materials, strategies, and challenges

Huang, Wenhui; Ding, Shenglong; Zhao, Xi-Yuan; Li, Kai; Guo, Hai-Tao; Zhang, Mingzhu; Gu, Qi

doi:10.1016/j.mtbio.2023.100639

Cited by 14 publications

(11 citation statements)

References 236 publications

(273 reference statements)

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“…Although fish collagen peptides (FCPs) have been used as a dietary supplement, little is known about how they affect cellular function in the human body [62]. ECM replacements can significantly affect cell proliferation and function based on recent research [36,63]. These extracellular matrixes, however, are mainly used in a general sense and are not yet tailored to certain cell types [63].…”

Section: Collagen As a Biomaterials For Tissue Engineeringmentioning

confidence: 99%

“…ECM replacements can significantly affect cell proliferation and function based on recent research [36,63]. These extracellular matrixes, however, are mainly used in a general sense and are not yet tailored to certain cell types [63]. This paper focuses on ECM-based coating substrates tailored to the individual needs of skin, skeletal muscle, and liver cell cultures [63].…”

Section: Collagen As a Biomaterials For Tissue Engineeringmentioning

confidence: 99%

“…These extracellular matrixes, however, are mainly used in a general sense and are not yet tailored to certain cell types [63]. This paper focuses on ECM-based coating substrates tailored to the individual needs of skin, skeletal muscle, and liver cell cultures [63]. With ongoing advancements, neural tissue engineering (NTE) indicates significant potential to treat a number of debilitating neurological illnesses [5].…”

Section: Collagen As a Biomaterials For Tissue Engineeringmentioning

confidence: 99%

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Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging

Rahman,

Rehmani,

Pirvu

et al. 2024

Marine Drugs

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Aging is closely associated with collagen degradation, impacting the structure and strength of the muscles, joints, bones, and skin. The continuous aging of the skin is a natural process that is influenced by extrinsic factors such as UV exposure, dietary patterns, smoking habits, and cosmetic supplements. Supplements that contain collagen can act as remedies that help restore vitality and youth to the skin, helping combat aging. Notably, collagen supplements enriched with essential amino acids such as proline and glycine, along with marine fish collagen, have become popular for their safety and effectiveness in mitigating the aging process. To compile the relevant literature on the anti-aging applications of marine collagen, a search and analysis of peer-reviewed papers was conducted using PubMed, Cochrane Library, Web of Science, and Embase, covering publications from 1991 to 2024. From in vitro to in vivo experiments, the reviewed studies elucidate the anti-aging benefits of marine collagen, emphasizing its role in combating skin aging by minimizing oxidative stress, photodamage, and the appearance of wrinkles. Various bioactive marine peptides exhibit diverse anti-aging properties, including free radical scavenging, apoptosis inhibition, lifespan extension in various organisms, and protective effects in aging humans. Furthermore, the topical application of hyaluronic acid is discussed as a mechanism to increase collagen production and skin moisture, contributing to the anti-aging effects of collagen supplementation. The integration of bio-tissue engineering in marine collagen applications is also explored, highlighting its proven utility in skin healing and bone regeneration applications. However, limitations to the scope of its application exist. Thus, by delving into these nuanced considerations, this review contributes to a comprehensive understanding of the potential and challenges associated with marine collagen in the realm of anti-aging applications.

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Section: Collagen As a Biomaterials For Tissue Engineeringmentioning

confidence: 99%

Section: Collagen As a Biomaterials For Tissue Engineeringmentioning

confidence: 99%

Section: Collagen As a Biomaterials For Tissue Engineeringmentioning

confidence: 99%

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Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging

Rahman,

Rehmani,

Pirvu

et al. 2024

Marine Drugs

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“…Collagen nanofiber scaffolds can gradually degrade in the body and integrate with newly formed tissue. This is beneficial in reducing complications such as the displacement and rejection of implants [ 141 ].…”

Section: Nanofiber Scaffold Technologymentioning

confidence: 99%

Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing

Jiang

Zheng

et al. 2023

Pharmaceutics

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Nanofiber scaffolds have emerged as a revolutionary drug delivery platform for promoting wound healing, due to their unique properties, including high surface area, interconnected porosity, excellent breathability, and moisture absorption, as well as their spatial structure which mimics the extracellular matrix. However, the use of nanofibers to achieve controlled drug loading and release still presents many challenges, with ongoing research still exploring how to load drugs onto nanofiber scaffolds without loss of activity and how to control their release in a specific spatiotemporal manner. This comprehensive study systematically reviews the applications and recent advances related to drug-laden nanofiber scaffolds for skin-wound management. First, we introduce commonly used methods for nanofiber preparation, including electrostatic spinning, sol–gel, molecular self-assembly, thermally induced phase separation, and 3D-printing techniques. Next, we summarize the polymers used in the preparation of nanofibers and drug delivery methods utilizing nanofiber scaffolds. We then review the application of drug-loaded nanofiber scaffolds for wound healing, considering the different stages of wound healing in which the drug acts. Finally, we briefly describe stimulus-responsive drug delivery schemes for nanofiber scaffolds, as well as other exciting drug delivery systems.

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“…Tissue engineering is a highly multidisciplinary field that aims to substitute, repair, and replace damaged tissue in neurologic diseases, combining scaffolds, cells, and bioactive molecules, both in vitro and in vivo [ 1 , 2 , 3 , 4 ]. The combined effect of these three components offers advanced opportunities for tissue regeneration [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Injectable Hydrogels for Nervous Tissue Repair—A Brief Review

Politrón-Zepeda,

Fletes-Vargas,

Rodríguez-Rodríguez

2024

Gels

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The repair of nervous tissue is a critical research field in tissue engineering because of the degenerative process in the injured nervous system. In this review, we summarize the progress of injectable hydrogels using in vitro and in vivo studies for the regeneration and repair of nervous tissue. Traditional treatments have not been favorable for patients, as they are invasive and inefficient; therefore, injectable hydrogels are promising for the treatment of damaged tissue. This review will contribute to a better understanding of injectable hydrogels as potential scaffolds and drug delivery system for neural tissue engineering applications.

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Collagen for neural tissue engineering: Materials, strategies, and challenges

Cited by 14 publications

References 236 publications

Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging

Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging

Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing

Injectable Hydrogels for Nervous Tissue Repair—A Brief Review

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