External Beam Radiotherapy for Extensive Genital Condyloma Acuminate: a Role in Selected Patients?

Dhadda, A.S.; Anand, Anjana; Boynton, Carole A.; Chan, Stephen Y.

doi:10.1016/j.clon.2007.08.016

Cited by 3 publications

(2 citation statements)

References 2 publications

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“…Dhadda et al . [9] described a case of condyloma acuminatum of the anogenital region that resolved during radiotherapy treatment for vulvar cancer, which has some parallels with our case. The 42‐year‐old patient had previously been treated with electrocautery, surgical resection, cryosurgery, laser surgery, topical podophyllin and imiquimod, but with little success.…”

Section: Discussionsupporting

confidence: 77%

Complete resolution of urinary bladder condyloma acuminatum following definitive chemoradiotherapy for anal cancer

White¹,

Donnellan²,

Leong³

2011

BJU International

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Section: Discussionsupporting

confidence: 77%

Complete resolution of urinary bladder condyloma acuminatum following definitive chemoradiotherapy for anal cancer

White¹,

Donnellan²,

Leong³

2011

BJU International

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“…Several other wart treatments, including cryosurgery, laser surgery, topical podophyllin, imiquimod, and surgical resection have been attempted. 19 In this case, with an unusual histological subtype, surgery may be considered for many reasons. Local treatment can't be used, due the bladder involvement, moreover radiotherapy is generally avoided in order to avoid the risk of secondary cancers related to radiotherapy for benign gynecological conditions.…”

Section: Discussionmentioning

confidence: 99%

Aggressive Behavior of Warty Squamous Cell Carcinoma of the Vagina Associated with Uterine Prolapsed: Unusual Report

Bouhani

Zemni

Sakhri

et al. 2021

Clin Med Insights Case Rep

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Warty squamous cell carcinoma (WSCC), is a rare variant of squamous cell carcinoma that occurs mostly in younger women, but can occur in old women. It is due to human papillomavirus (HPV) infection. This rare entity has been described in several organs such as vulva, cervix, and penis. To the best of our knowledge WSCC of vagina associated with the third-degree of uterine prolapse has never been reported in the literature. We present an exceptional case of WSCC of vagina occurred in a 77-year-old woman with long disease duration. The physical exam found a large ulcer-budding lesion of the middle and lower third of the vagina that depends on the left vaginal wall. The full work-up concluded to stage IVA of FIGO classification, due to the bladder involvement. The patient underwent a hysterectomy, bilateral salpingo-oophorectomy, bilateral pelvic node dissection, left partial cystectomy with left ureteral reimplantation and total vaginectomy, followed by adjuvant radiotherapy. The patient had no recurrence during 8 years of regular follow-up. WSCC can express locally aggressive behavior, such we reported; despite it appears to be less aggressive than the typical well-differentiated squamous cell carcinoma. That leads to individualize WSCC from other verruciform neoplasms.

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Giant condyloma acuminatum surgical management: a case report and literature review

Al-Ghamdi,

Alfalah,

Anwer

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Condyloma acuminatum (CA) or genital warts, represents a rare sexually transmitted disease caused by the human papillomavirus. Infection occurs when host basal cells are exposed to viral infection through a damaged epithelial barrier, during sexual intercourse, or due to other minor skin abrasions. Giant condyloma acuminatum (GCA) has a higher rate of malignant transformation than CA. Case presentation: We are presenting a 44-year-old single gentleman known as a smoker, hepatitis B positive, vitiligo, and hypercholesteromia. He was an alcoholic and had multiple heterosexual relationships abroad. Referred from the dermatology clinic, complaining of genital warts that had increased in size for 10 years. Clinical discussion: CA management includes local applications like imiquimod and podophyllotoxin and clinician-administered treatments such as cryotherapy, surgical excision, electrosurgery, and CO2 laser therapy. Other options, such as interferon, radiotherapy, or chemotherapy, are available. The selection of therapy should be individualized and based upon consideration of the extent of the disease, patient preference, cost, adverse effects, treatment availability, and the response to previous treatments. Complete surgical excision is the treatment of choice for GCA. Conclusion: We present a patient with GCA in the perianal area that was surgically treated with an excellent outcome.

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External Beam Radiotherapy for Extensive Genital Condyloma Acuminate: a Role in Selected Patients?

Cited by 3 publications

References 2 publications

Complete resolution of urinary bladder condyloma acuminatum following definitive chemoradiotherapy for anal cancer

Complete resolution of urinary bladder condyloma acuminatum following definitive chemoradiotherapy for anal cancer

Aggressive Behavior of Warty Squamous Cell Carcinoma of the Vagina Associated with Uterine Prolapsed: Unusual Report

Giant condyloma acuminatum surgical management: a case report and literature review

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