Extensive pure venous malformations in the upper or lower limb: A review of 27 cases

Coagulation Disorders in Patients With Venous Malformation of the Limbs and Trunk

“…10,11 This LIC is associated with painful thrombotic episodes inside the VM, resulting in the formation of multiple phleboliths. Because of the consumption of coagulation factors, the anticoagulant effect of fibrin degradation products, and the exhaustion of hyperactivated platelets, this lifelong LIC leads to hemorrhagic complication when a surgical procedure is performed on the VM area or when trauma involves this region.…”

“…Recurrent hemarthrosis alters the joint cartilage, similar to arthropathy in individuals with hemophilia. 10 This study of a large group of patients was specifically undertaken to better define the clinical characteristics of the VM involving the limbs and trunk and to investigate the incidence, importance, and outcomes of the VM-associated LIC in these distinctive locations. …”

Arteriovenous Malformation in CLOVES Syndrome

“…AVM can induce consumptive coagulation by activating cytokines as part of a systemic inflammatory response or by causing the release of procoagulant substances [19,20]. AVM are lined by dysplastic cells exposed to stagnated blood, which can trigger chronic localized intravascular coagulation [21]. DIC has been reported in Klippel-Trenaunay patients; a syndrome of slowflow vascular malformations and skeletal and soft tissue hypertrophy [22,23].…”

Protocolo de actuación ante hemangiomas y/o malformaciones vasculares

“…En las malformaciones vasculares venosas o mixtas extensas se ha descrito una coagulación intravascular localizada hasta en el 88% de los pacientes 10 . Este trastorno, en función de la gravedad puede producir hemorragias y trombosis en situación basal y empeorar claramente con algunos tratamientos (inmovilización postquirúrgica, escleroterapia).…”