Coagulation Disorders in Patients With Venous Malformation of the Limbs and Trunk

Mazoyer, E.; Enjolras, O; Bisdorff, Annouk; Perdu, Jérome; Wassef, Michel; Drouet, Ludovic

doi:10.1001/archderm.144.7.861

Cited by 184 publications

(166 citation statements)

References 14 publications

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“…Angiography is also a useful modality for defining extent of disease, especially when identifying deep or small VMs, such as intracranial sinus pericranii or gastrointestinal VM. [12][13][14][15][16][17][18][19][20] In the present case, phleboliths were seen on plain radiography and were suggestive of vascular anomaly with slow flow rate. Whereas, by direct phlebography the lesion was seen draining the regional vein.…”

Section: Investigationsupporting

confidence: 49%

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Multiple Low Flow Vascular Malformation with Phleboliths – A Case Report

Prakash¹,

Naik²,

Dhanavel³

2017

JYP

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Section: Investigationsupporting

confidence: 49%

“…1 Although it is felt that there is no gender predisposition, one series did find a female preponderance. 15 The oral cavity (59%) and nasal cavity (35%) were the most common locations. Tongue and lips are sites for the lesion involving oral cavity, and nasal septum in the nasal cavity.…”

Section: Epidemiologymentioning

confidence: 99%

Multiple Low Flow Vascular Malformation with Phleboliths – A Case Report

Prakash¹,

Naik²,

Dhanavel³

2017

JYP

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“…VM are accompanied by spontaneous thrombosis and thrombolysis (19,20). Coagulation disorders are the result of chronic venous blood stagnation within the large irregular vascular spaces, leading to activation of coagulation cascade reactions following production of thrombin, the conversion of fibrinogen into fibrin, which induces the blood clot formation.…”

Section: Discussionmentioning

confidence: 99%

A Diagnostic Program of Vascular Tumor and Vascular Malformations in Children According to Modern Classification

Benzar

2017

Acta Med. (Hradec Kralove, Czech Repub.)

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A B ST R AC T The aim of the study was to analyze the cohort of inpatient children with vascular anomalies according to the globally accepted classification introduced by the ISSVA. Methods: The study included 205 inpatient children within the time period of the years 2010-2015. Types of vascular anomalies (VAs), age of patients, diagnostic procedures, and anatomical localization of VAs were analyzed. Results: 65 patients of first year of life had vascular tumors, with prevalence of infantile hemangiomas (IHs) in 57 (87.7%) patients. 45 children had IHs localized within soft tissues, whereas 7 patients suffered from IHs of the liver, and 5 children from IHs of the respiratory tract. Most patients with soft tissue IHs were diagnosed only with ultrasound; СT or MRI diagnostics were performed on 5 (8.8%) patients, and biopsy was carried out in 2 (4.4%) children. Vascular malformations (VM) were diagnosed in 140 (68.3%) patients. Ultrasound investigation (US) was the screening method. MRI was performed to confirm the diagnosis of low-flow VM, whereas for high-flow VM CT angiography and selective angiography were useful. Venous malformations were diagnosed in 17 (12.1%) patients, and 112 (80.0%) had cystic LM, among them children under the age of 2 years prevailed. Arteriovenous malformations were diagnosed in 5 (3.8%) patients, ages 2-14 years. Conclusions: Clinical manifestations of vascular anomalies have clear age features. Among hospitalized children vascular tumors add up to 31.7% and VM -up to 68.3%.

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“…At presentation, her hemoglobin was 3.9 gm/dL, platelet count 70,000/mm the combined lesions are named according to the affected vessel, e.g., capillarovenous and capillaro-lymphatico-VM (Flow Chart 1). 7 Venous malformation can also occur in Klippel-Trenaunay syndrome (capillaro-lymphatico-VM with limb hypertrophy) and Maffucci syndrome (multiple endochondromas associated with multiple hemangioendothelioma and high incidence of malignancy). 8,9 Our patient presented with multiple congenital vascular malformation present at lateral canthus of right eye, left parotid gland, anterolateral aspect of right knee joint, left gluteal region, left knee joint anteriorly, abdominal wall, inferior angle of right scapula, dorsum of left foot, and sole of left foot along with slow-flow VM present in parotid.…”

Section: Case Reportmentioning

confidence: 99%