Extensive Ossification in a Pulmonary Plasmacytoma

Abstract

Extramedullary plasmacytomata form an interesting group of tumours, the nature and behaviour of which are still not well understood. The majority of such tumours are situated in the pharynx, upper respiratory tract, and conjunctiva (Hellwig, 1943). Less frequent sites have been the thyroid, intestine, ovary, and kidney. A study of the literature available to us has revealed that so far 18 cases (Ackerman, 1953 ;Brunn, 1939;Carson, Ackerman, and Maltby, 1955;Childress and Adie, 1950;Cotton and Penido, 1952;Gordon and Walker, 1944;Hill and White, 1953;Kilburn and Schmidt, 1960;Kuley and Kuntman, 1951;Lane, Krohn, Kolozsi, and Whitehead, 1955;Lisovskii and Grindzhiliya, 1962;Rambaldi, Odoardi, and Vergine, 1959;Robson and Knudsen, 1959;Romanoff and Milwidsky, 1962;Rozsa and Frieman, 1953;Tchertkoff, Lee, and Wagner, 1963;Uvarova and Dubrovaskii, 1962;Viszloy and Dar6czy, 1960) Examination of the cardiovascular system revealed that the praecordium was bulging slightly. The apex beat was palpable in the left fifth space in the midclavicular line. On percussion the left border of the heart could not be made out because of dullness all over the left side of the chest. The heart sounds were normal. No murmurs were audible.On examination of the respiratory system the trachea was central. The movements of the left side of the chest were diminished. Tactile vocal fremitus was also diminished on the left side. On percussion the entire left side of the chest was dull, and on auscultation the breath sounds were diminished in intensity and occasional rales were present.Examination of the abdomen showed that both the spleen and the liver were palpable two fingerbreadths below the costal margin. Other systems were normal.

The relation between chronic polyneuropathy and osteosclerotic myeloma.

“…Attention has already been drawn to the sclerosis by Small et al (1964). We cannot say whether the sclerosis is that seen with 'myeloproliferative' disorders (Videbaek, 1956;Brody, Beizer, and Schwartz, 1964), whether new bone is formed by the myeloma (Kinare, Parulkar, Panday, and Sen, 1965), or whether it is merely a non-specific bone reaction. The interesting fact is that when Landry-Guillain-Barre polyneuropathy complicates myeloma, 'typical' myeloma is unusual.…”

Lymphosarcoma of the lung with monoclonal (IgM) gammopathy.A clinicopathologic, histochemical, immunologic, and ultrastructural study

“…25.6~ 67 Solitary plasmacytoma of the lung,21. 35,64 bronchial carcinoma,14.32* 60 and chronic lung disease4 have all been reported in association with a monoclonal gammopathy.…”