Extensive cerebral invasion of a basal cell carcinoma of the scalp

Schroeder, Malte; Kestlmeier, R; Schlegel, Jürgen; Trappe, A. E

doi:10.1053/ejso.2000.1100

Cited by 30 publications

(26 citation statements)

References 4 publications

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“…In the literature few case reports are reported, particularly with invasion of supratentorial structures (2,4). After review of the literature this is the first case report describing such an intracranial infiltration of BCC with this localization and extension.…”

Section: Discussionmentioning

confidence: 82%

“…BCC of the head and neck are the most common, (1,3,5) particularly on the face and scalp due to the sun exposure and thus ultraviolet radiation, which is considered to be the main cause of developing BCC. Intracranial invasion is very rare and has been reported only in a few cases (2,4). All these case reports describe intracranial infiltration of structures with supratentorial localization.…”

Section: Introductionmentioning

confidence: 99%

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Intracranial basal cell carcinoma with extensive invasion of the skull base

Mahvash

2014

Turkish Neurosurgery

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Intracranial invasion of basal cell carcinoma is very rare. A case of a 71-year-old male patient is presented with extensive invasion of middle and posterior fossae, with nearly complete destruction of the petrous bone, involving cerebellopontine angle and cranial nerves by recurrent basal cell carcinoma of the auricular region on the right side. The clinical manifestation was cerebrospinal fluid otorrhoea, facial nerve palsy and trigeminal nerve impairment with hypoesthesia. The patient underwent surgery by combined retroauricular and temporal approach to the skull base. Adjuvant radiation of residual tumor and former tumor recurrence region was performed. MRI studies performed annually show no progress of the tumor. Our patient reports a good quality of life without new neurological deficits 6 years after surgery. Attention should be paid to the malignant nature of basal cell carcinoma making follow up care necessary. In indicated cases in which incomplete excision cannot be excepted and risk factors exist, follow up with CT or/and MRI should be performed to evaluate the infiltrative and invasive character of aggressive basal cell carcinoma and to rule out bone or cerebral infiltration. KEywORDS: Basal cell carcinoma, Intracranial invasion, Skull base ÖZBazal hücreli karsinomun intrakraniyal invazyonu çok nadirdir. Orta ve posterior fossada belirgin invazyon, petröz kemiğin hemen hemen tümüyle harabiyeti, serebellopontin açı ve kraniyal sinirlerin sağ tarafta auriküler bölgede nüks bazal hücreli karsinom tarafından tutulduğu 71 yaşında bir erkek olguyu sunuyoruz. Klinik bulgular serebrospinal sıvı otoresi, fasiyal sinir palsisi ve hipoesteziyle birlikte trigeminal sinir tutulumu şeklindeydi. Hastada kafa kaidesine kombine retroauriküler ve temporal yaklaşımla cerrahi yapıldı. Kalan tümör ve daha önceki tümör nüks bölgesine adjuvan radyasyon uygulandı. Yılda bir yapılan MRG çalışmaları tümörde ilerleme göstermedi. Hastamız cerrahiden 6 yıl sonra yeni bir nörolojik defisit olmadan iyi bir yaşam kalitesi bildirmektedir. Bazal hücreli karsinomun malign özelliğine dikkat edilmelidir ve takip gereklidir. Tam olmayan eksizyonun kabul edilemeyeceği ve risk faktörlerinin bulunduğu, endike olan olgularda agresif bazal hücreli karsinomun infiltratif ve invaziv karakterini değerlendirmek ve kemik veya serebral infiltrasyonu ekarte etmek açısından BT ve/veya MRG ile takip yapılmalıdır. ANAHTAR SÖZCÜKLER:Bazal hücreli karsinom, İntrakraniyal invazyon, Kafa kaidesi

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Section: Discussionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Intracranial basal cell carcinoma with extensive invasion of the skull base

Mahvash

2014

Turkish Neurosurgery

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“…(Sahl, 1994). Radiation therapy can be considered as adjuvant or palliative option (Schroeder, et al, 2001;Burns, et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

“…Other hystologic aspect, that may be consider as minor criteria are: inflammatory infiltrate, fibrosis, palisadism and increased of mitotic rate (Schroeder, et al, 2001;Walling, et al, 2004). Appear intuitive that a high number of mitotic figures are linked to a rapid cellular turnover, but the role of inflammatory infiltration has to be clarify.…”

Section: Risk Factormentioning

confidence: 99%