Extension of the <i>in vivo</i> haploid induction system from diploid maize to hexaploid wheat

Liu, Chenxu; Zhong, Yu; Qi, Xiaozhe; Chen, Ming; Liu, Zong-Kai; Chen, Chen; Tian, Xiaolong; Li, Jinlong; Jiao, Yanyan; Wang, Dong; Wang, Yuwen; Li, Mengran; Xin, Mingming; Liu, Wenxin; Jin, Weiwei; Chen, Shaojiang

doi:10.1111/pbi.13218

Cited by 104 publications

(78 citation statements)

References 10 publications

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“…GE is a type of novel, fast, effective, and precise genetic engineering whereby DNA can be deleted, inserted, modified, or replaced in the target region of the genome ( Cho et al., 2013 , Bortesi and Fischer, 2015 ). It has been widely applied in crop plants, and significant examples include those leading to generation of DH lines through maternal haploid induction in maize ( Dong et al., 2018 ), wheat ( Liu et al., 2019 ), and rice ( Yao et al., 2018 ). One of the GE applications in plant breeding is to weed out the deleterious or bad alleles by GE-based targeted mutagenesis, which is not possible in conventional selection due to LD between favorable and deleterious alleles and limited population sizes ( Gibson, 2012 , Yang et al., 2017 , Hirsch and Springer, 2018 ).…”

Section: Integrating Gs With Modern Breeding Technologiesmentioning

confidence: 99%

Enhancing Genetic Gain through Genomic Selection: From Livestock to Plants

Liu

et al. 2020

Plant Communications

163

131

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Although long-term genetic gain has been achieved through increasing use of modern breeding methods and technologies, the rate of genetic gain needs to be accelerated to meet humanity's demand for agricultural products. In this regard, genomic selection (GS) has been considered most promising for genetic improvement of the complex traits controlled by many genes each with minor effects. Livestock scientists pioneered GS application largely due to livestock's significantly higher individual values and the greater reduction in generation interval that can be achieved in GS. Large-scale application of GS in plants can be achieved by refining field management to improve heritability estimation and prediction accuracy and developing optimum GS models with the consideration of genotype-by-environment interaction and non-additive effects, along with significant cost reduction. Moreover, it would be more effective to integrate GS with other breeding tools and platforms for accelerating the breeding process and thereby further enhancing genetic gain. In addition, establishing an open-source breeding network and developing transdisciplinary approaches would be essential in enhancing breeding efficiency for small- and medium-sized enterprises and agricultural research systems in developing countries. New strategies centered on GS for enhancing genetic gain need to be developed.

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Section: Integrating Gs With Modern Breeding Technologiesmentioning

confidence: 99%

Enhancing Genetic Gain through Genomic Selection: From Livestock to Plants

Liu

et al. 2020

Plant Communications

163

131

View full text Add to dashboard Cite

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“…In maize a frame-shift mutation in MATRILINEAL (MTL), a pollen-specific phospholipase exclusively localized to sperm cytoplasm, triggered an increase in the haploid induction rate ( [172]; see also [173,174]), with similar results in Indica rice [175] and wheat [176]. Even though MTL is not directly involved in parthenogenesis, it shows that pollen-specific genes may mediate the formation of haploid seeds.…”

Section: Parthenogenetic Mutantsmentioning

confidence: 80%

Apomixis Technology: Separating the Wheat from the Chaff

Hojsgaard

2020

Genes

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Projections indicate that current plant breeding approaches will be unable to incorporate the global crop yields needed to deliver global food security. Apomixis is a disruptive innovation by which a plant produces clonal seeds capturing heterosis and gene combinations of elite phenotypes. Introducing apomixis into hybrid cultivars is a game-changing development in the current plant breeding paradigm that will accelerate the generation of high-yield cultivars. However, apomixis is a developmentally complex and genetically multifaceted trait. The central problem behind current constraints to apomixis breeding is that the genomic configuration and molecular mechanism that initiate apomixis and guide the formation of a clonal seed are still unknown. Today, not a single explanation about the origin of apomixis offer full empirical coverage, and synthesizing apomixis by manipulating individual genes has failed or produced little success. Overall evidence suggests apomixis arise from a still unknown single event molecular mechanism with multigenic effects. Disentangling the genomic basis and complex genetics behind the emergence of apomixis in plants will require the use of novel experimental approaches benefiting from Next Generation Sequencing technologies and targeting not only reproductive genes, but also the epigenetic and genomic configurations associated with reproductive phenotypes in homoploid sexual and apomictic carriers. A comprehensive picture of most regulatory changes guiding apomixis emergence will be central for successfully installing apomixis into the target species by exploiting genetic modification techniques.

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“…The gene was characterized almost simultaneously by three research groups and called MATRILINEAL (MTL; [112]), NOT LIKE DAD (NLD; [115]), and ZmPLA1 [116]. Haploid induction can be induced in rice by knocking out the gene OsMATL [117], and TaMTL in wheat [138]. Combining either the MiMe strategy with MATL successfully produced clonal seed, but at exceptionally low frequencies (Table 2; [105,139]).…”

Section: Mimicking Gametophytic Apomixismentioning

confidence: 99%

Can We Use Gene-Editing to Induce Apomixis in Sexual Plants?

Scheben

Hojsgaard²

2020

Genes

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Apomixis, the asexual formation of seeds, is a potentially valuable agricultural trait. Inducing apomixis in sexual crop plants would, for example, allow breeders to fix heterosis in hybrid seeds and rapidly generate doubled haploid crop lines. Molecular models explain the emergence of functional apomixis, i.e., apomeiosis + parthenogenesis + endosperm development, as resulting from a combination of genetic or epigenetic changes that coordinate altered molecular and developmental steps to form clonal seeds. Apomixis-like features and synthetic clonal seeds have been induced with limited success in the sexual plants rice and maize by using gene editing to mutate genes related to meiosis and fertility or via egg-cell specific expression of embryogenesis genes. Inducing functional apomixis and increasing the penetrance of apomictic seed production will be important for commercial deployment of the trait. Optimizing the induction of apomixis with gene editing strategies that use known targets as well as identifying alternative targets will be possible by better understanding natural genetic variation in apomictic species. With the growing availability of genomic data and precise gene editing tools, we are making substantial progress towards engineering apomictic crops.

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Extension of the in vivo haploid induction system from diploid maize to hexaploid wheat

Cited by 104 publications

References 10 publications

Enhancing Genetic Gain through Genomic Selection: From Livestock to Plants

Enhancing Genetic Gain through Genomic Selection: From Livestock to Plants

Apomixis Technology: Separating the Wheat from the Chaff

Can We Use Gene-Editing to Induce Apomixis in Sexual Plants?

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