Expression of TLR genes in Black Bengal goat (Capra hircus) during different seasons

Paul, Avishek; Dangi, S.S.; Gupta, Mahesh; Singh, Jai Pal; Thakur, Neeraj; Naskar, S.; Nanda, Pramod Kumar; Mohanty, Nihar Nalini; Das, Asit; Bandopadhayay, S.; Das, Bikash; Sarkar, Mihir

doi:10.1016/j.smallrumres.2015.01.011

Cited by 29 publications

(17 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to our finding, Paul et al (2015) also reported significantly higher TLR1 expression during exposure to summer season induced heat stress in Black Bengal goats. Further, Tirumurugaan et al (2010) also reported increased expression of TLR1 in different organs such as uterus, skin, lymph node, PBMC, and lungs of heatstressed Kanni breed goats.…”

Section: Discussionsupporting

confidence: 91%

“…These findings suggest the superiority of Salem Black breed to maintain immune status as compared to even other indigenous goat breeds. Similar to our findings there are also reports of higher expression of TLR4 in response to heat stress in different species (Ju et al 2014;Paul et al 2015;Bharati et al 2017). This difference between these studies could be attributed to the difference in the magnitude of heat stress as well as the difference in the adaptive capacity of different breeds.…”

Section: Discussionsupporting

confidence: 90%

“…The expression pattern of TLR6 also was similar to that of TLR1, TLR4, and TLR5 in the current study. Similar results of significantly higher TLR6 expression pattern were also reported in other species (Plain et al 2010;Paul et al 2015;Srikanth et al 2017). These authors attributed this to the superior thermo-tolerance of these animals.…”

Section: Discussionsupporting

confidence: 85%

“…Moreover, the presence of these TLRs in organs and their expression pattern in response to specific stimuli is one of the factors determining the disease resistance capability of an animal (Tirumurugaan et al 2010). Further, Paul et al (2015) suggest that goats under heat-stressed state showed significant up-regulation of few TLRs which play an important role in stimulating the innate immune response.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Quantitative analysis of expression patterns of different cell surface Toll-like receptor genes imparting heat stress resilience to indigenous Osmanabadi and Salem Black goat breeds

Savitha

Kumar

Sejian

et al. 2020

JABB

View full text Add to dashboard Cite

The study was conducted to establish the differences in the expression pattern of different cell surface toll-likereceptors (TLRs) between indigenous Osmanabadi and Salem Black goats subjected to summer season induced heat stress. The primary objective of the study is to assess the thermotolerance ability of these two breeds based on maintaining the immune status during exposure to heat stress. The results indicated that the expression of TLR1, TLR4, TLR5, TLR6, and TLR10 genes in both the breeds showed different expression pattern. The expression pattern of all these genes did not differed between the control (OC) and heat stress (OHS) group in Osmanabadi breed but significantly higher (P<0.05) expression of these genes were reported in heat stress group (SBHS) as compared to control group (SBC) in Salem Black breed. However, the striking difference was established in the expression pattern of TLR2 between these breeds. The TLR expression was significantly higher in heat stress group of Osmanabadi breed. But TLR2 did not express in Salem Back breed. The higher expression of most of the cell surface TLRs in the SBHS group as compared to OHS group indicates the superior resilient capacity of Salem Black goats to maintain immune status even during exposure to adverse environmental condition. Further, these TLRs could serve as indicators to reflect better thermo-tolerance of Salem Black breed over Osmanabadi breed.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Quantitative analysis of expression patterns of different cell surface Toll-like receptor genes imparting heat stress resilience to indigenous Osmanabadi and Salem Black goat breeds

Savitha

Kumar

Sejian

et al. 2020

JABB

View full text Add to dashboard Cite

show abstract

“…HSP can be detected in all organisms (Kakobsson et al, 2013;Zhang et al, 2014;Gautam et al, 2013;Murphy 2013). Paul et al (2015) studies have proved that heat stimulation can activate the expression of HSP60 and HSP70, and then activate the immune systems of goat. Adly et al (2006) reported that HSP27 plays a very important role in the hair follicle cycle.…”

Section: Discussionmentioning

confidence: 99%

HOXC13 and HSP27 Expression in Skin and the Periodic Growth of Secondary Fiber Follicles from Longdong Cashmere Goats Raised in Different Production Systems

Wang

et al. 2017

The Anatomical Record

View full text Add to dashboard Cite

This experiment was conducted to identify periodic changes in secondary follicles (SFs) over one year of extensive (grazed) and intensive (housed and fed supplement) farming of Longdong cashmere goats. One-year old goats (n = 24, 12 extensively fed and 12 intensively fed) were studied. The diameter, depth, density, activity, and ultra-structural features of SFs were assessed using light microscopy and transmission electron microscopy. HOXC13 and HSP27 expression were studied using immunohistochemistry and immunofluorescence method. The anagen stage in the extensively grazed goats was from April to September, but was longer (April to October) in the housed, supplementary fed group. The depth and activity of the SF in anagen and catagen differed (P < 0.05) between the groups. HSP27 and HOXC13 protein were present in both the epidermis and dermis, with HSP27 immunoreactivity highest in the hair shaft (HS), outer root sheath (ORS) and inner root sheath (IRS). HOXC13 expression was prominent in both the eprdermis and ORS. HSP27 and HOXC13 expression were prominent during anagen, and less so during catagen and telogen. In anagen, HSP27 expression in the HS, IRS, and ORS of the extensively fed group was higher than in the intensively fed group (p < 0.05). In contrast, HOXC13 expression in HS, IRS and ORS of the extensively fed group was lower than in the intensively fed group (P < 0.05). This suggests the growth of cashmere is influenced by nutrition and that housed goats could be used in cashmere production. Anat Rec, 301:742-752, 2018. © 2017 Wiley Periodicals, Inc.

show abstract

Expression Dynamics of Heat Shock Proteins (HSP) in Livestock under Thermal Stress

Dangi

Bharati

Samad

et al. 2017

Heat Shock Proteins

View full text Add to dashboard Cite

Expression of TLR genes in Black Bengal goat (Capra hircus) during different seasons

Cited by 29 publications

References 37 publications

Quantitative analysis of expression patterns of different cell surface Toll-like receptor genes imparting heat stress resilience to indigenous Osmanabadi and Salem Black goat breeds

Quantitative analysis of expression patterns of different cell surface Toll-like receptor genes imparting heat stress resilience to indigenous Osmanabadi and Salem Black goat breeds

HOXC13 and HSP27 Expression in Skin and the Periodic Growth of Secondary Fiber Follicles from Longdong Cashmere Goats Raised in Different Production Systems

Expression Dynamics of Heat Shock Proteins (HSP) in Livestock under Thermal Stress

Contact Info

Product

Resources

About