Expression of Stearoyl Co-enzyme A desaturase (SCD) gene during the juvenile age in layer chicken

Abstract

Stearoyl-CoA desaturase (SCD) is key enzyme in the production of triglycerides and cholesterol. Present study was conducted to know the expression pattern of the Stearoyl-CoA desaturase (SCD) gene in liver during juvenile age (0 day, 14th day, 28th day and 42nd day) in layer birds. Expression of SCD gene increased from the day of hatch to 42nd day, as the body weight and fat deposition increased. The mRNA expression levels of SCD gene during day 0 was differed significantly (P less than 0.05) with expression levels during other juvenile ages. When compared with SCD expression levels on the day 0 expression levels were up-regulated by 8198.64, 7245.99 and 5587.77 folds over day 14, 28 and 42 respectively. Serum concentration of triglycerides and cholesterol were found to be proportional to the expression levels of SCD gene in liver. It is concluded that SCD expression varied among different age groups during juvenile stages and had significant association with serum triglycerides and cholesterol concentration in layer chicken.

Expression Profile of Acetyl CoA Carboxylase Beta (ACACB) Gene during the Pre and Post-hatch Period in Chicken

“…In both control broiler and Aseel, the ACTRIIB gene expressed at ED7, ED11 and ED16 (Vishnu et al 2017). Similar results were also found in the post-hatch period in layer chicken line, where the highest and lowest expression level of the SCD gene was found on the 2nd (40.75) and 6th week (27.75), respectively (Sagar et al, 2019). In the control layer, the expression of ACACA gene was up-regulated during 2nd, 4th and 6th weeks of age, when compared to the day one post-hatch period (Prasad et al 2018b).…”