Express high-sensitive detection of ochratoxin A in food by a lateral flow immunoassay based on magnetic biolabels

Орлов, А. В.; Malkerov, Juri A.; Novichikhin, D.O.; Znoyko, S.L.; Никитин, П. И.

doi:10.1016/j.foodchem.2022.132427

Cited by 30 publications

(19 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At the same time, according to some data, there is reason to believe that super-enhancers can be much more ancient, if compared exempli gratia with stress response proteins in multicellular organisms. It should be noted that advancements in understanding the molecular mechanisms of diseases (particularly oncological diseases [ 217 , 218 , 219 , 220 ]) as well as the study of intermolecular interactions through high-performance optical methods [ 221 , 222 , 223 ], the ultrasensitive determination of biomolecules using magnetic nanomarkers [ 224 , 225 , 226 , 227 ] or label-free biosensors [ 228 , 229 , 230 ], and the processing of genome-wide data through high-performance methods such as cloud computing [ 231 , 232 ] may provide new opportunities for comprehending the role of SEs, potentially leading to the revision of their definition.…”

Section: Discussionmentioning

confidence: 99%

Experimental Validation and Prediction of Super-Enhancers: Advances and Challenges

Kravchuk

Ashniev

Гладкова

et al. 2023

Cells

Self Cite

View full text Add to dashboard Cite

Super-enhancers (SEs) are cis-regulatory elements of the human genome that have been widely discussed since the discovery and origin of the term. Super-enhancers have been shown to be strongly associated with the expression of genes crucial for cell differentiation, cell stability maintenance, and tumorigenesis. Our goal was to systematize research studies dedicated to the investigation of structure and functions of super-enhancers as well as to define further perspectives of the field in various applications, such as drug development and clinical use. We overviewed the fundamental studies which provided experimental data on various pathologies and their associations with particular super-enhancers. The analysis of mainstream approaches for SE search and prediction allowed us to accumulate existing data and propose directions for further algorithmic improvements of SEs’ reliability levels and efficiency. Thus, here we provide the description of the most robust algorithms such as ROSE, imPROSE, and DEEPSEN and suggest their further use for various research and development tasks. The most promising research direction, which is based on topic and number of published studies, are cancer-associated super-enhancers and prospective SE-targeted therapy strategies, most of which are discussed in this review.

show abstract

Section: Discussionmentioning

confidence: 99%

Experimental Validation and Prediction of Super-Enhancers: Advances and Challenges

Kravchuk

Ashniev

Гладкова

et al. 2023

Cells

Self Cite

View full text Add to dashboard Cite

show abstract

“…covalently immobilized an anti-OTA mAb on MNPs for rapid biorecognition with a detection limit of 11 pg/mL during 20 min OTA registration by LFA. The high specificity, reproducibility, and reproducibility of the method in corn meal were also validated …”

Section: Microbial Toxinsmentioning

confidence: 98%

Magnetic Nanoseparation Technology for Efficient Control of Microorganisms and Toxins in Foods: A Review

Kang

Shi

Sun

et al. 2022

J. Agric. Food Chem.

View full text Add to dashboard Cite

Outbreaks of foodborne diseases mediated by food microorganisms and toxins remain one of the leading causes of disease and death worldwide. It not only poses a serious threat to human health and safety but also imposes a huge burden on health care and socioeconomics. Traditional methods for the removal and detection of pathogenic bacteria and toxins in various samples such as food and drinking water have certain limitations, requiring a rapid and sensitive strategy for the enrichment and separation of target analytes. Magnetic nanoparticles (MNPs) exhibit excellent performance in this field due to their fascinating properties. The strategy of combining biorecognition elements with MNPs can be used for fast and efficient enrichment and isolation of pathogens. In this review, we describe new trends and practical applications of magnetic nanoseparation technology in the detection of foodborne microorganisms and toxins. We mainly summarize the biochemical modification and functionalization methods of commonly used magnetic nanomaterial carriers and discuss the application of magnetic separation combined with other instrumental analysis techniques. Combined with various detection techniques, it will increase the efficiency of detection and identification of microorganisms and toxins in rapid assays.

show abstract

“…7). 74 It can also be used for the detection of other living organisms such as the major fish allergen parvalbumin, (Pa) with a qualitative and quantitative detection LOD of 5 mg mL −1 and 0.046 mg mL −1 , 75 and Vibrio cholerae in shrimp with a quantitative LOD of 46 CFU per ml. 76 Histamine is a harmful biogenic amine in wine.…”

Section: Applicationmentioning

confidence: 99%

Magnetic nanoprobe-enabled lateral flow assays: recent advances

Ying

Guo

Jie

2023

Analyst

View full text Add to dashboard Cite

show abstract

Express high-sensitive detection of ochratoxin A in food by a lateral flow immunoassay based on magnetic biolabels

Cited by 30 publications

References 39 publications

Experimental Validation and Prediction of Super-Enhancers: Advances and Challenges

Experimental Validation and Prediction of Super-Enhancers: Advances and Challenges

Magnetic Nanoseparation Technology for Efficient Control of Microorganisms and Toxins in Foods: A Review

Magnetic nanoprobe-enabled lateral flow assays: recent advances

Contact Info

Product

Resources

About