Exposure of children and mothers to organophosphate esters: Prediction by house dust and silicone wristbands

Xie, Qitong; Guan, Qingxia; Li, Liangzhong; Ho, Cheuk Lam; Liu, Xiaotu; Hou, Sen; Chen, Da

doi:10.1016/j.envpol.2021.117011

Cited by 17 publications

(23 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The cost of applying this technique can vary heavily depending on the amount and purity of solvents used per a number of wristbands or their weight. Agitation of a wash was obtained most commonly via the use of a magnetic plate stirrer [ 65 ], an orbital (at the speed of 60–120 rotations per minute) [ 18 , 20 , 71 ], platform (60 rpm) [ 68 ], or overhead (60 rpm) shaker [ 24 ], with one study using ultrasonication for that purpose [ 78 ]. Performing an agitated wash can be considered more accessible, as it requires the use of common laboratory equipment, unlike Soxhlet extraction.…”

Section: Chemical Analysis Of Silicone Wristbandsmentioning

confidence: 99%

“…This stage of sample preparation had been carried out in the reviewed research papers by washing post-exposure wristbands in a solvent. Most commonly a cycle (or series of cycles) of agitated WB wash(es) were performed, with the use of either an orbital shaker [ 18 , 20 , 36 , 45 , 48 , 59 , 67 , 68 , 69 , 75 , 77 ], an overhead shaker [ 24 , 71 ], a magnetic stir plate [ 65 ], Soxhlet extraction [ 51 ], or sonication [ 21 , 28 , 47 , 58 , 63 , 70 , 72 , 74 , 76 , 78 ]. The most frequently applied solvent of choice was ethyl acetate [ 20 , 24 , 55 ].…”

Section: Chemical Analysis Of Silicone Wristbandsmentioning

confidence: 99%

“…Moreover, discrepancies in presentation of quantitative results exist. Some researchers use analyte mass per entire wristband (e.g., Dixon et al [ 48 ], Xie et al [ 78 ]), whereas others share results as analyte mass per unit mass of the wristband (usually per one gram; e.g., Hammel et al [ 72 ], Wise et al [ 74 ]). These differences may hinder comparisons between the studies [ 51 ].…”

Section: Qualitative and Quantitative Analysismentioning

confidence: 99%

“…These differences may hinder comparisons between the studies [ 51 ]. Because wristbands of various sizes are used (e.g., Gibson et al [ 62 ], Quintana et al [ 50 ], Xie et al [ 78 ]), we recommend using analyte mass per unit mass of the wristband as a more versatile approach.…”

Section: Qualitative and Quantitative Analysismentioning

confidence: 99%

“…Inconsistent results were obtained in studies investigating silicone WBs–urine relationship while assessing exposure to OPEs. For instance, low and statistically insignificant correlations were observed between triphenyl phosphate (TPHP) in WBs and its metabolite, diphenyl phosphate (DPHP), in urine [ 49 , 51 , 72 , 78 ], except for Wise et al [ 74 ] ( Table S2 ). DPHP, however, is not a specific (unique) metabolite of TPHP, so concurrent exposure to other OPEs possibly overshadowed the true link.…”

Section: Comparison Of Wristbands With Other Matricesmentioning

confidence: 99%

See 4 more Smart Citations

Silicone Wristbands in Exposure Assessment: Analytical Considerations and Comparison with Other Approaches

Wacławik

Rodzaj

Wielgomas

2022

IJERPH

View full text Add to dashboard Cite

Humans are exposed to numerous potentially harmful chemicals throughout their lifetime. Although many studies have addressed this issue, the data on chronic exposure is still lacking. Hence, there is a growing interest in methods and tools allowing to longitudinally track personal exposure to multiple chemicals via different routes. Since the seminal work by O’Connell et al. (2014), silicone wristbands (WBs) have been increasingly used to facilitate human exposure assessment, as using WBs as a wearable sampler offers new insights into measuring chemical risks involved in many ambient and occupational scenarios. However, the literature lacks a detailed overview regarding methodologies being used; a comprehensive comparison with other approaches of personal exposure assessment is needed as well. Therefore, the aim of this review is fourfold. First, we summarize hitherto conducted research that employed silicone WBs as personal passive samplers. Second, all pre-analytical and analytical steps used to obtain exposure data are discussed. Third, we compare main characteristics of WBs with key features of selected matrices used in exposure assessment, namely urine, blood, hand wipes, active air sampling, and settled dust. Finally, we discuss future needs of research employing silicone WBs. Our work shows a variety of possibilities, advantages, and caveats associated with employment of silicone WBs as personal passive samplers. Although further research is necessary, silicone WBs have already been proven valuable as a tool for longitudinal assessment of personal exposure.

show abstract

Section: Chemical Analysis Of Silicone Wristbandsmentioning

confidence: 99%

Section: Chemical Analysis Of Silicone Wristbandsmentioning

confidence: 99%

Section: Qualitative and Quantitative Analysismentioning

confidence: 99%

Section: Qualitative and Quantitative Analysismentioning

confidence: 99%

Section: Comparison Of Wristbands With Other Matricesmentioning

confidence: 99%

See 3 more Smart Citations

Silicone Wristbands in Exposure Assessment: Analytical Considerations and Comparison with Other Approaches

Wacławik

Rodzaj

Wielgomas

2022

IJERPH

View full text Add to dashboard Cite

show abstract

Triphenyl phosphate‐induced macrophages dysfunction by activation TLR4‐mediated ERK/NF‐κB pathway

Lin

Zhang

et al. 2023

Environmental Toxicology

View full text Add to dashboard Cite

Triphenyl phosphate (TPHP) is one of the most widely used organic phosphorus flame retardants and is ubiquitous in the environment. Studies have been reported that TPHP may lead to obesity, neurotoxicity and reproductive toxicity, but its impact on the immune system is almost blank. The present study was aimed to investigate the potential immunotoxicity of TPHP on macrophages and its underlying mechanism. The results demonstrated for the first time that TPHP (12.5, 25, and 50 μM)‐induced F4/80+CD11c+ phenotype of RAW 264.7 macrophages, accompanied by increased mRNA levels of inflammatory mediators, antigen‐presenting genes (Cd80, Cd86, and H2‐Aa), and significantly enhanced the phagocytosis of macrophage. Meanwhile, TPHP increased the expression of Toll‐like receptor 4 (TLR4), and its co‐receptor CD14, leading to significant activation of the downstream ERK/NF‐κB pathway. However, co‐exposure of cells to TAK‐242, a TLR4 inhibitor, suppressed TPHP‐induced F4/80+CD11c+ phenotype, and down‐regulated inflammatory mediators and antigen‐presentation related genes, via blocked the TLR4/ERK/NF‐κB pathway. Taken together, our results suggested that TPHP could induce macrophage dysfunction through activating TLR4‐mediated ERK/NF‐κB signaling pathway, and it may be the potential reason for health‐threatening consequences.

show abstract

Association of organophosphate ester exposure with cardiovascular disease among US adults: Cross-sectional findings from the 2011–2018 National Health and Nutrition Examination Survey

Guo

Xia

et al. 2022

Chemosphere

View full text Add to dashboard Cite

Exposure of children and mothers to organophosphate esters: Prediction by house dust and silicone wristbands

Cited by 17 publications

References 65 publications

Silicone Wristbands in Exposure Assessment: Analytical Considerations and Comparison with Other Approaches

Silicone Wristbands in Exposure Assessment: Analytical Considerations and Comparison with Other Approaches

Triphenyl phosphate‐induced macrophages dysfunction by activation TLR4‐mediated ERK/NF‐κB pathway

Association of organophosphate ester exposure with cardiovascular disease among US adults: Cross-sectional findings from the 2011–2018 National Health and Nutrition Examination Survey

Contact Info

Product

Resources

About