“…Were we to have built the model within the R-RTW cohort only, using the variables identified in the larger data (age, physical demands, opioid prescription, employer doubt about work-relatedness of injury, and healthcare provider's poor recovery expectations, union membership, availability of a return-to-work program, participation in a rehabilitation program, and communication of functional ability Both the model fit of the prediction rule (derived from the larger dataset) as validated in the smaller sample as well as the duration on benefits (median of 57 days) were comparable between the two samples, which confirms earlier 6,657 workers on full benefits on first day of injury 15 not accessible due to security restrictions 1,796 workers still on benefits (either/both total or/and partial benefits) at 4 weeks -1,615 cases Form 6 prior to 4 weeks -1,776 cases Form 7 prior to 4 weeks -1,685 cases Form 8 prior to 4weeks -1,796 cases with pharma data prior to 4 weeks Focus on those assessed at 4 weeks and still off work: 1,442 total benefits (100% wage replacement benefits) -113 also part of R-RTW cohort study -1310 cases Form 6 prior to 4 weeks -1424 cases Form 7 prior to 4 weeks -1354 cases Form 8 prior to 4 weeks -1442 cases with pharma data prior to 4 weeks 0 lost to follow up (benefits data only) analyses that the R-RTW is a representative sample of injured workers [7]. Still, a prediction rule developed in a small dataset is likely not applicable to the general population.The model fit of the improved prediction rule for time on benefits was better compared to the fit presented in studies in similar settings, which reported a discriminative ability of 0.80 [34] and 0.76 [35]. It was better compared to others reporting an AUC of 0.63 [36] and 0.69 when validating the Orebro Musculoskeletal Screening Questionnaire in a Canadian workers' compensation setting [37].…”